Imaging of Plaque With Magnetic Resonance Imaging (MRI)
Completed · Not applicable
Conditions studied: Arterial Occlusive Disease
In brief
This study aims to develop and refine the use of an intravascular wire to image plaque in the aorta, iliac and femoral artery using MRI. This project aims to use this increased resolution to identify the features within the plaque that is known to be associated with increased risk of plaque and vessel occlusion. The hypothesis is Intravascular MRI can detect and measure changes in response to therapy over time in the critical features in plaques in peripheral arteries of patients with atherosclerosis.
Key facts
- Study ID
- NCT00115856
- Run by
- Brigham and Women's Hospital
- People needed
- 20
- Starts
- 2001-01-01
- Expected to finish
- 2005-06-01
- Last updated by the study team
- 2015-08-03
Who can join
Age: 25 and older, up to 80. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Male and female adults (aged 25-80) seen at the Brigham and Women's Hospital (BWH) clinic who have known arterial disease who consent to cannulation of the femoral artery for this research.
- Patients in the prespecified age group who are scheduled to undergo a clinically indicated heart or peripheral catheterization at the BWH catheterization (cath) lab who will have a tube (sheath) already positioned in their femoral artery
- Patient must be in stable condition with regard to symptoms, vital signs and the monitored electrocardiogram
You may not qualify if…
- Unstable symptoms, vital signs or electrocardiogram after the heart cath
- Any complications during the heart cath (eg., bleeding, angina, arrhythmias, technical difficulties cannulating the femoral artery)
- Creatinine >2.0mg/dl
- Pregnancy
- Contraindications to anticoagulation
- Patients with a metal implant, pacemaker, cardiac defibrillator, metal fragments in the eye, bullets/metal objects in the body
Where it is running
- Brigham and Womens Hospital — Boston, Massachusetts, United States
Full record on ClinicalTrials.gov
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