Laser-Assisted Versus Conventional Intracytoplasmic Sperm Injection

Completed · Not applicable

Conditions studied: Infertility, Infertility, Male

In brief

Laser-assisted intracytoplasmic sperm injection (ICSI) has been suggested as a more effective alterative to conventional ICSI when this method of insemination is indicated for patients undergoing in vitro fertilization (IVF). Laser-assisted ICSI differs from conventional ICSI in that a laser is used to drill a small hole through the hard outer coating surrounding an egg before the injection needle containing a single sperm is inserted into the egg. The hole eliminates compression of the egg that normally occurs with conventional ICSI, and thus may reduce the chance of damage. Laser-assisted ICSI is hypothesized to result in increased egg survival, and perhaps improved embryo quality, compared to conventional ICSI.

Key facts

Study ID

NCT00114725

Run by

Shady Grove Fertility Reproductive Science Center

People needed

60

Starts

2004-03-01

Expected to finish

2004-10-01

Last updated by the study team

2005-06-24

Who can join

Age: 18 and older, up to 45. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Diagnosis of infertility
• Scheduled for IVF with ICSI

You may not qualify if…

• Retrieval of fewer than 6 mature oocytes

Where it is running

• Shady Grove Fertility Reproductive Science Center — Rockville, Maryland, United States

Full record on ClinicalTrials.gov

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