BVAIT: B-Vitamin Atherosclerosis Intervention Trial

Completed · Phase 2/Phase 3

Conditions studied: Atherosclerosis

In brief

The purpose of this study is to examine whether vitamin B supplementation will reduce the progression of early atherosclerosis in individuals over 40 years old and without clinical evidence of cardiovascular disease (CVD).

Key facts

Study ID

NCT00114400

Run by

National Institute on Aging (NIA)

People needed

506

Starts

2000-11-01

Expected to finish

2007-02-01

Last updated by the study team

2009-12-11

Who can join

Age: 40 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Male or female (postmenopausal)
• 40 years or older
• Fasting plasma homocysteine 8.5 micromoles per liter (µmol/L) or greater

You may not qualify if…

• Any clinical signs or symptoms of cardiovascular disease (CVD)
• Diabetes mellitus or fasting serum glucose 140 mg/dL or greater
• Triglyceride (TG) levels 500mg/dL or greater
• Serum creatinine greater than 1.6 mg/dL
• Uncontrolled hypertension (systolic blood pressure 160 mmHg or greater and/or diastolic blood pressure 100 mmHg or greater)
• Thyroid disease (untreated)
• Life threatening disease with prognosis less than 5 years
• Alcohol intake greater than 5 drinks per day (1 drink = 1 1/2 oz distilled spirits, 4 oz wine, or 12 oz beer) or substance abuse (intravenous drug use, cocaine use)

Where it is running

• Atherosclerosis Research Unit, Division of Cardiovascular Medicine, Department of Medicine — Los Angeles, California, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.