Cytarabine With or Without VNP40101M in Treating Patients With Relapsed Acute Myeloid Leukemia
Completed · Phase 3 · Has a placebo group
Conditions studied: Leukemia
In brief
RATIONALE: Drugs used in chemotherapy, such as cytarabine and VNP40101M, work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more cancer cells. PURPOSE: This randomized phase III trial is studying cytarabine and VNP40101M to see how well they work compared to cytarabine alone in treating patients with relapsed acute myeloid leukemia.
Key facts
- Study ID
- NCT00112554
- Run by
- Vion Pharmaceuticals
- People needed
- 420
- Starts
- 2005-03-01
- Expected to finish
- 2008-03-01
- Last updated by the study team
- 2013-11-06
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Ottawa Hospital Regional Cancer Centre - General Campus — Ottawa, Ontario, Canada
- Princess Margaret Hospital — Toronto, Ontario, Canada
- Centre Hospitalier Regional de Besancon - Hopital Jean Minjoz — Besançon, France
- Hopital Edouard Herriot — Lyon, France
- Marseille Institute of Cancer - Institut J. Paoli and I. Calmettes — Marseille, France
- CHR Hotel Dieu — Nantes, France
- Hopital Haut Leveque — Pessac, France
- Charite - Universitaetsmedizin Berlin - Campus Benjamin Franklin — Berlin, Germany
- Medizinische Universitaetsklinik I at the University of Cologne — Cologne, Germany
- Universitaetsfrauenklinik Frankfurt — Frankfurt, Germany
- Universitatsklinikum Heidelberg — Heidelberg, Germany
- Klinikum der Universitaet Muenchen - Grosshadern Campus — Munich, Germany
- Medizinische Klinik und Poliklinik A - Universitaetsklinikum Muenster — Münster, Germany
- University Wurzburg — Würzburg, Germany
- Evaggelismos Hospital — Athens, Greece
- University of Patras Medical School — Rio Patras, Greece
- University Medical Center Groningen — Groningen, Netherlands
- Medical University of Gdansk — Gdansk, Poland
- Medical University of Lodz — Lodz, Poland
- Centrum Onkologii Ziemi Lubelskiez — Lublin, Poland
- Wojskowy Instytut Medyczny — Warsaw, Poland
- Institute of Haematology and Blood Transfusion — Warsaw, Poland
- Clinical Centre of Serbia — Belgrade, Serbia
- Clinical Centre Nis — Niš, Serbia
- Capital District Health Authority Center for Clinical Research — Halifax, Nova Scotia, Canada
Full record on ClinicalTrials.gov
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