Study of AQ4N in Patients With Non Hodgkin's Lymphoma, Chronic Lymphocytic Leukemia, or Small Lymphocytic Leukemia
Status unconfirmed · Phase 1/Phase 2
Conditions studied: Non-Hodgkin's Lymphoma, Chronic Lymphocytic Leukemia, Small Lymphocytic Leukemia
In brief
The purpose of this study is to find answers to the following questions: * What is the largest dose of AQ4N that can be given safely one time every three weeks for 24 weeks? * What are the side effects of AQ4N when given according to this schedule? * How much AQ4N is in the blood at certain times after administration and how does the body get rid of the drug? * Will AQ4N help treat lymphoid cancer?
Key facts
- Study ID
- NCT00109356
- Run by
- Novacea
- People needed
- 55
- Starts
- 2005-03-01
- Expected to finish
- 2007-03-01
- Last updated by the study team
- 2007-05-07
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Diagnosis of Non-Hodgkin's Lymphoma, Chronic Lymphocytic Leukemia, or Small Lymphocytic Leukemia
- Tumor specimen available for evaluation (please provide 10 unstained slides)
- Relapse after receiving primary treatment and at least one salvage therapy
- Eastern Cooperative Oncology Group (ECOG) performance status ≤ 2
- Laboratory test measurements
- Females of childbearing potential must have a negative pregnancy test result within 3 days prior to the first dose and must agree to use an effective contraceptive method during the course of the study and for 6 months following the last dose of study drug.
- Older than 18 years of age
- Available for periodic blood sampling
You may not qualify if…
- Certain cardiac problems
- Previous donor stem cell transplant
- Known HIV, Hepatitis B, Hepatitis C infection
- Previous chemotherapy, radiation or other investigational drug treatments within 4 weeks of first planned dose of study drug
- Major surgery within four weeks of first planned dose of study drug
- Any active viral, bacterial, or fungal infection within four weeks of first planned dose of study drug
- Pregnant or breastfeeding
Where it is running
- Weill Medical College of Cornell University/ New York Presbyterian Hospital — New York, New York, United States
Full record on ClinicalTrials.gov
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