The Effects of Risperidone and Olanzapine on Thinking

Completed · Phase 4

Conditions studied: Schizophrenia, Psychotic Disorders

In brief

The goal of this research is to find ways to maximize the benefits of antipsychotic medications for cognition. Hypothesis: Risperidone and olanzapine will show greater benefits than conventional medications on assessments of social cognition, particularly affect perception and social perception.

Key facts

Study ID

NCT00108368

Run by

US Department of Veterans Affairs

Starts

2003-10-01

Expected to finish

2006-03-01

Last updated by the study team

2009-01-21

Who can join

Age: 18 and older, up to 60. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Diagnosed with schizophrenia disorder by a DSM IV.
• Competent to sign informed consent
• No history of poor response to Risperdal and Zyprexa
• No organic brain disease

You may not qualify if…

• Mental retardation or any chronic medical illness which results in the patient not being appropriate for a switch to Risperdal or Zyprexa.

Where it is running

• VA Greater Los Angeles Healthcare System — Los Angeles, California, United States

Full record on ClinicalTrials.gov

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