Docetaxel, Carboplatin, and Pegfilgrastim in Treating Patients Who Are Undergoing Surgery for Stage II or Stage III Breast Cancer
Completed · Phase 2
Conditions studied: Breast Cancer
In brief
RATIONALE: Drugs used in chemotherapy, such as docetaxel and carboplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Colony-stimulating factors, such as pegfilgrastim, may increase the number of immune cells found in bone marrow or peripheral blood and may help the immune system recover from the side effects of chemotherapy. Giving docetaxel and carboplatin together with pegfilgrastim before surgery may shrink the tumor so that it can be removed. PURPOSE: This phase II trial is studying how well giving docetaxel and carboplatin together with pegfilgrastim works in treating patients who are undergoing surgery for stage II or stage III breast cancer.
Key facts
- Study ID
- NCT00107510
- Run by
- Alliance for Clinical Trials in Oncology
- People needed
- 58
- Starts
- 2005-08-01
- Last updated by the study team
- 2016-07-06
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Kewanee Hospital — Kewanee, Illinois, United States
- McDonough District Hospital — Macomb, Illinois, United States
- Trinity Medical Center - East — Moline, Illinois, United States
- Study site — Moline, Illinois, United States
- BroMenn Regional Medical Center — Normal, Illinois, United States
- Community Cancer Center — Normal, Illinois, United States
- Community Hospital of Ottawa — Ottawa, Illinois, United States
- Oncology Hematology Associates of Central Illinois, PC - Ottawa — Ottawa, Illinois, United States
- Cancer Treatment Center at Pekin Hospital — Pekin, Illinois, United States
- Proctor Hospital — Peoria, Illinois, United States
- CCOP - Illinois Oncology Research Association — Peoria, Illinois, United States
- Oncology Hematology Associates of Central Illinois, PC - Peoria — Peoria, Illinois, United States
- Methodist Medical Center of Illinois — Peoria, Illinois, United States
- OSF St. Francis Medical Center — Peoria, Illinois, United States
- Illinois Valley Community Hospital — Peru, Illinois, United States
- Perry Memorial Hospital — Princeton, Illinois, United States
- St. Margaret's Hospital — Spring Valley, Illinois, United States
- Carle Cancer Center at Carle Foundation Hospital — Urbana, Illinois, United States
- Mayo Clinic Scottsdale — Scottsdale, Arizona, United States
- Mayo Clinic - Jacksonville — Jacksonville, Florida, United States
- Rush-Copley Cancer Care Center — Aurora, Illinois, United States
- St. Joseph Medical Center — Bloomington, Illinois, United States
- Graham Hospital — Canton, Illinois, United States
- Memorial Hospital — Carthage, Illinois, United States
- Joliet Oncology-Hematology Associates, Limited - West — Joliet, Illinois, United States
Full record on ClinicalTrials.gov
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