Study of XL999 in Adults With Solid Tumors

Completed · Phase 1

Conditions studied: Cancer

In brief

The purpose of this study is to assess the safety and tolerability of XL999 in adults with advanced solid tumors.

Key facts

Study ID

NCT00104117

Run by

Symphony Evolution, Inc.

People needed

52

Starts

2004-11-01

Expected to finish

2008-10-01

Last updated by the study team

2010-02-19

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Advanced solid tumor
• Cancer that has progressed on currently available therapies
• Life expectancy of >3 months
• Adequate bone marrow, liver, and kidney function
• Willing to use accepted method of contraception during the course of the study
• Negative pregnancy test (females)
• Written informed consent

You may not qualify if…

• Chemotherapy within 4-6 weeks of the start of treatment (depending on the therapy)
• Radiotherapy within 4 weeks of the start of treatment
• Subjects with known brain metastasis
• Uncontrolled medical disorder such as infection or cardiovascular disease
• Subjects known to be HIV positive
• Pregnant or breastfeeding women

Where it is running

• Case Western Reserve University, Univserzity Hospitals of Cleveland — Cleveland, Ohio, United States
• Cancer Therapy and Research Center, Institute for Drug Development — San Antonio, Texas, United States

Full record on ClinicalTrials.gov

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