Cetuximab and Cisplatin in Treating Patients With Advanced, Persistent, or Recurrent Cervical Cancer
Completed · Phase 2
Conditions studied: Cervical Cancer
In brief
RATIONALE: Monoclonal antibodies, such as cetuximab, can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread. Others find tumor cells and help kill them or carry tumor-killing substances to them. Cetuximab may also help cisplatin work better by making tumor cells more sensitive to the drug. Drugs used in chemotherapy, such as cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving cetuximab together with cisplatin may be a better way to block tumor growth. PURPOSE: This phase II trial is studying how well giving cetuximab together with cisplatin works in treating patients with advanced, persistent, or recurrent cervical cancer.
Key facts
- Study ID
- NCT00101192
- Run by
- Gynecologic Oncology Group
- People needed
- 76
- Starts
- 2004-09-01
- Last updated by the study team
- 2014-03-17
Who can join
Age: 18 and older. Sex: female. Healthy volunteers: not accepted.
Where it is running
- Providence Saint Joseph Medical Center - Burbank — Burbank, California, United States
- USC/Norris Comprehensive Cancer Center and Hospital — Los Angeles, California, United States
- Curtis and Elizabeth Anderson Cancer Institute at Memorial Health University Medical Center — Savannah, Georgia, United States
- Indiana University Melvin and Bren Simon Cancer Center — Indianapolis, Indiana, United States
- Kansas Masonic Cancer Research Institute at the University of Kansas Medical Center — Kansas City, Kansas, United States
- Ochsner Cancer Institute at Ochsner Clinic Foundation — New Orleans, Louisiana, United States
- Christus Schumpert Cancer Treatment Center — Shreveport, Louisiana, United States
- University of Mississippi Cancer Clinic — Jackson, Mississippi, United States
- Fox Chase Virtua Health Cancer Program at Virtua West Jersey — Voorhees Township, New Jersey, United States
- Wake Forest University Comprehensive Cancer Center — Winston-Salem, North Carolina, United States
- MetroHealth Cancer Care Center at MetroHealth Medical Center — Cleveland, Ohio, United States
- Cleveland Clinic Taussig Cancer Center — Cleveland, Ohio, United States
- Oklahoma University Cancer Institute — Oklahoma City, Oklahoma, United States
- Cancer Care Associates - Midtown Tulsa — Tulsa, Oklahoma, United States
- Fox Chase Cancer Center - Philadelphia — Philadelphia, Pennsylvania, United States
- McGlinn Family Regional Cancer Center at Reading Hospital and Medical Center — Reading, Pennsylvania, United States
- University of Texas Medical Branch — Galveston, Texas, United States
- M. D. Anderson Cancer Center at University of Texas — Houston, Texas, United States
Full record on ClinicalTrials.gov
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