Immune and Endocrine Function in Post-Traumatic Stress Disorder

Completed

Conditions studied: Post-Traumatic Stress Disorders

In brief

This is a study investigating immune function and relationships to the hypothalamic-pituitary-adrenal (HPA) axis in Post-traumatic stress disorder (PTSD) compared to controls without PTSD. The study involves 99 adult veterans and civilian subjects over a 3 year period. The study involves measuring immune and neuroendocrine parameters from blood samples obtained before and after a dexamethasone suppression test. The aim of the study is to determine whether immune alterations exist in PTSD and whether the immune-HPA axis interactions in this disorder are different from non-PTSD subjects with the future aim of studying whether immune dysregulation in PTSD may be linked to the increased risk for medical and psychiatric comorbidity in this population.

Key facts

Study ID
NCT00100490
Run by
US Department of Veterans Affairs
Starts
1999-10-01
Expected to finish
2002-09-01
Last updated by the study team
2009-01-21

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

Where it is running

Full record on ClinicalTrials.gov

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