Thalidomide and Temozolomide in Relapsed or Progressive CNS Disease or Neuroblastoma

Completed · Phase 2

Conditions studied: Central Nervous System Tumor, Pediatric, Neuroblastoma

In brief

RATIONALE: Thalidomide may stop the growth of tumor cells by stopping blood flow to the tumor. Drugs used in chemotherapy, such as temozolomide, work in different ways to stop tumor cells from dividing so they stop growing or die. Combining thalidomide with temozolomide may kill more tumor cells. PURPOSE: This phase II trial is studying the effectiveness of combining thalidomide with temozolomide in treating young patients who have relapsed or progressive brain tumors or recurrent neuroblastoma.

Key facts

Study ID
NCT00098865
Run by
Dana-Farber Cancer Institute
People needed
15
Starts
2002-09-01
Expected to finish
2010-06-01
Last updated by the study team
2014-10-07

Who can join

Age: any, up to 21. Sex: any. Healthy volunteers: not accepted.

Where it is running

Full record on ClinicalTrials.gov

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