Rituximab and Combination Chemotherapy in Treating Patients With Newly Diagnosed Primary CNS Lymphoma
Completed · Phase 2
Conditions studied: Lymphoma
In brief
RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Monoclonal antibodies, such as rituximab, can block cancer growth in different ways. Some block the ability of cancer cells to grow and spread. Others find cancer cells and help kill them or carry cancer-killing substances to them. Giving rituximab with combination chemotherapy may kill more cancer cells. PURPOSE: This phase II trial is studying how well rituximab given with combination chemotherapy works in treating patients with newly diagnosed primary CNS lymphoma.
Key facts
- Study ID
- NCT00098774
- Run by
- Alliance for Clinical Trials in Oncology
- People needed
- 47
- Starts
- 2004-10-01
- Expected to finish
- 2014-09-01
- Last updated by the study team
- 2016-07-06
Who can join
Age: any. Sex: any. Healthy volunteers: not accepted.
Where it is running
- UCSF Helen Diller Family Comprehensive Cancer Center — San Francisco, California, United States
- Tunnell Cancer Center at Beebe Medical Center — Lewes, Delaware, United States
- CCOP - Christiana Care Health Services — Newark, Delaware, United States
- University of Chicago Cancer Research Center — Chicago, Illinois, United States
- Fort Wayne Medical Oncology and Hematology — Fort Wayne, Indiana, United States
- Hematology Oncology Associates of the Quad Cities — Bettendorf, Iowa, United States
- Menorah Medical Center — Overland Park, Kansas, United States
- Saint Luke's Hospital - South — Overland Park, Kansas, United States
- Shawnee Mission Medical Center — Shawnee Mission, Kansas, United States
- Union Hospital Cancer Program at Union Hospital — Elkton MD, Maryland, United States
- Masonic Cancer Center at University of Minnesota — Minneapolis, Minnesota, United States
- Truman Medical Center - Hospital Hill — Kansas City, Missouri, United States
- Saint Luke's Cancer Institute at Saint Luke's Hospital — Kansas City, Missouri, United States
- St. Joseph Medical Center — Kansas City, Missouri, United States
- North Kansas City Hospital — Kansas City, Missouri, United States
- Parvin Radiation Oncology — Kansas City, Missouri, United States
- CCOP - Kansas City — Kansas City, Missouri, United States
- Research Medical Center — Kansas City, Missouri, United States
- Saint Luke's East - Lee's Summit — Lee's Summit, Missouri, United States
- Liberty Hospital — Liberty, Missouri, United States
- Heartland Regional Medical Center — Saint Joseph, Missouri, United States
- Cancer Institute of New Jersey at Cooper - Voorhees — Voorhees Township, New Jersey, United States
- Stony Brook University Cancer Center — Stony Brook, New York, United States
- SUNY Upstate Medical University Hospital — Syracuse, New York, United States
- Arthur G. James Cancer Hospital and Solove Research Institute at Ohio State University Medical Center — Columbus, Ohio, United States
Full record on ClinicalTrials.gov
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