Pemetrexed Disodium in Treating Patients With Recurrent or Persistent Low-Risk Gestational Trophoblastic Tumor After a Molar Pregnancy

Stopped early · Phase 2

Conditions studied: Gestational Trophoblastic Tumor

In brief

RATIONALE: Drugs used in chemotherapy, such as pemetrexed disodium, work in different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: This phase II trial is studying how well pemetrexed disodium works in treating patients with recurrent or persistent low-risk gestational trophoblastic tumor after a molar pregnancy.

Key facts

Study ID

NCT00096187

Run by

Gynecologic Oncology Group

People needed

55

Starts

2005-07-01

Last updated by the study team

2018-04-12

Who can join

Age: any, up to 120. Sex: female. Healthy volunteers: not accepted.

Where it is running

• Lurleen Wallace Comprehensive Cancer at University of Alabama-Birmingham — Birmingham, Alabama, United States
• Providence Saint Joseph Medical Center - Burbank — Burbank, California, United States
• Chao Family Comprehensive Cancer Center at University of California Irvine Medical Center — Orange, California, United States
• Robert H. Lurie Comprehensive Cancer Center at Northwestern University — Chicago, Illinois, United States
• Hinsdale Hematology Oncology Associates — Hinsdale, Illinois, United States
• CCOP - Carle Cancer Center — Urbana, Illinois, United States
• Holden Comprehensive Cancer Center at University of Iowa — Iowa City, Iowa, United States
• St. John's Regional Health Center — Springfield, Missouri, United States
• Hulston Cancer Center at Cox Medical Center South — Springfield, Missouri, United States
• Cancer Institute of New Jersey at Cooper - Voorhees — Voorhees Township, New Jersey, United States
• Blumenthal Cancer Center at Carolinas Medical Center — Charlotte, North Carolina, United States
• Duke Comprehensive Cancer Center — Durham, North Carolina, United States
• Wilson Medical Center — Wilson, North Carolina, United States
• Charles M. Barrett Cancer Center at University Hospital — Cincinnati, Ohio, United States
• Case Comprehensive Cancer Center — Cleveland, Ohio, United States
• Cleveland Clinic Taussig Cancer Center — Cleveland, Ohio, United States
• Arthur G. James Cancer Hospital and Solove Research Institute at Ohio State University — Columbus, Ohio, United States
• Riverside Methodist Hospital Cancer Care — Columbus, Ohio, United States
• Hillcrest Cancer Center at Hillcrest Hospital — Mayfield Heights, Ohio, United States
• Lake/University Ireland Cancer Center — Mentor, Ohio, United States
• Oklahoma University Cancer Institute — Oklahoma City, Oklahoma, United States
• Rosenfeld Cancer Center at Abington Memorial Hospital — Abington, Pennsylvania, United States
• McGlinn Family Regional Cancer Center at Reading Hospital and Medical Center — Reading, Pennsylvania, United States
• Simmons Comprehensive Cancer Center at University of Texas Southwestern Medical Center - Dallas — Dallas, Texas, United States
• UMC Southwest Cancer and Research Center — Lubbock, Texas, United States

Full record on ClinicalTrials.gov

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