Arsenic Trioxide and Etanercept in Treating Patients With Myelodysplastic Syndromes

Completed · Phase 1/Phase 2

Conditions studied: Leukemia, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Diseases

In brief

RATIONALE: Drugs used in chemotherapy, such as arsenic trioxide, work in different ways to stop cancer cells from dividing so they stop growing or die. Biological therapies such as etanercept may interfere with the growth of the cancer cells. Combining chemotherapy with biological therapy may kill more cancer cells. PURPOSE: This phase I/II trial is studying the side effects of giving arsenic trioxide together with etanercept and to see how well it works in treating patients with myelodysplastic syndromes.

Key facts

Study ID
NCT00093366
Run by
Fred Hutchinson Cancer Center
People needed
32
Starts
2004-06-01
Expected to finish
2006-07-01
Last updated by the study team
2011-11-30

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

Where it is running

Full record on ClinicalTrials.gov

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