Fish Oil and Alpha Lipoic Acid in Treating Alzheimer's Disease

Completed · Phase 1/Phase 2 · Has a placebo group

Conditions studied: Alzheimer's Disease, Oxidative Stress, Dementia, Hyperlipidemia, Inflammation

In brief

The purpose of this study is to determine the effect of fish oil and the antioxidant alpha lipoic acid on factors in the blood that are associated with the progression of Alzheimer's Disease (AD).

Key facts

Study ID

NCT00090402

Run by

Oregon Health and Science University

People needed

39

Starts

2004-04-01

Expected to finish

2007-08-01

Last updated by the study team

2017-07-21

Who can join

Age: 55 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Diagnosis of probable Alzheimer's Disease or mild cognitive impairment
• Mini Mental State Examination (MMSE) score between 18 and 26
• Clinical Dementia Rating (CDR) of 0.5 or 1.0
• Fluent in English

You may not qualify if…

• Use of lipid lowering medications
• Consumption of fish of more than twice a week
• Use of omega and alpha lipoic acid supplements
• Use of systemic corticosteroids, neuroleptics, anti-Parkinsonian agents, or narcotic analgesics
• Depression
• Any other serious health conditions that may interfere with the study
• Enrollment in another clinical trial

Where it is running

• Oregon Health and Science University — Portland, Oregon, United States

Full record on ClinicalTrials.gov

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