Mycophenolate Mofetil (MMF) for Treatment of Chronic Graft-versus-host Disease (GVHD)
Stopped early · Phase 3 · Has a placebo group
Conditions studied: Cancer
In brief
RATIONALE: Mycophenolate mofetil added to immunosuppressive treatment regimens may be effective in treating newly diagnosed chronic graft-versus-host disease caused by stem cell transplantation. It is not yet known whether immunosuppressive treatment regimens are more effective with or without mycophenolate mofetil in treating chronic graft-versus-host disease. PURPOSE: This randomized phase III trial is studying whether the addition of mycophenolate mofetil improves the efficacy of immunosuppressive treatment regimens in patients with newly diagnosed chronic graft-versus-host disease.
Key facts
- Study ID
- NCT00089141
- Run by
- Martin, Paul
- People needed
- 151
- Starts
- 2004-05-01
- Expected to finish
- 2008-09-01
- Last updated by the study team
- 2013-05-03
Who can join
Age: 4 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- City of Hope Comprehensive Cancer Center — Duarte, California, United States
- Stanford Cancer Center — Stanford, California, United States
- University of Florida Shands Cancer Center — Gainesville, Florida, United States
- University of Chicago Cancer Research Center — Chicago, Illinois, United States
- University of Michigan Comprehensive Cancer Center — Ann Arbor, Michigan, United States
- Masonic Cancer Center at University of Minnesota — Minneapolis, Minnesota, United States
- UNMC Eppley Cancer Center at the University of Nebraska Medical Center — Omaha, Nebraska, United States
- Hackensack University Medical Center Cancer Center — Hackensack, New Jersey, United States
- Oregon Health and Science University Cancer Institute — Portland, Oregon, United States
- Vanderbilt-Ingram Cancer Center — Nashville, Tennessee, United States
- Baylor University Medical Center - Dallas — Dallas, Texas, United States
- M. D. Anderson Cancer Center at University of Texas — Houston, Texas, United States
- Texas Transplant Institute — San Antonio, Texas, United States
- Fred Hutchinson Cancer Research Center — Seattle, Washington, United States
- University of Washington School of Medicine — Seattle, Washington, United States
- Princess Margaret Hospital — Toronto, Ontario, Canada
Full record on ClinicalTrials.gov
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