Maintaining Abstinence in Chronic Cigarette Smokers - 1

Completed · Phase 2 · Has a placebo group

Conditions studied: Tobacco Use Disorder

In brief

The purpose of this study is to evaluate the extended pharmacological and psychological treatment for chronic cigarette smokers.

Key facts

Study ID

NCT00087880

Run by

National Institute on Drug Abuse (NIDA)

People needed

407

Starts

2002-12-01

Expected to finish

2009-09-01

Last updated by the study team

2017-01-12

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Subjects are age 18 and over, currently smoking 10 or more cigarettes per day, and report a smoking history of at least 5 years in response to the question "How long have you been a regular smoker?"

You may not qualify if…

• History of seizure or head injury resulting in unconsciousness
• Any condition that might predispose to seizures (brain tumor or stroke)
• A current or history of anorexia nervosa or bulimia
• Any disease acutely life-threatening or so severe that the patient is judged unable to comply with the protocol
• Use of a protease inhibitor of MAO inhibitor within the last two week
• Current use of psychiatric drugs that would interfere with interpretation of study results, including antidepressants
• Treatment for alcohol dependence during the last year, or evidence of alcohol abuse so severe that the patient is judged potentially unable to comply with the protocol
• Patients who know they are leaving the Bay Area within the study period and non-English speakers will be excluded
• Suicidal or homicidal ideation
• Current major depression
• History of bipolar disorder
• Recent (within twelve months) myocardial infarction
• Any other medical condition that would contraindicate use of NRT or bupropion
• Physical limitation so severe that participation in a program of moderate exercise is not possible
• Pregnancy or lactation

Where it is running

• University California, San Francisco — San Francisco, California, United States

Full record on ClinicalTrials.gov

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