S0356 Oxaliplatin, 5-FU, Radiation Therapy (RT), Surgery for Pts With Stage II or III Cancer of Esophagus or Gastroesophageal (GE) Junction
Completed · Phase 2
Conditions studied: Esophageal Cancer
In brief
RATIONALE: Drugs used in chemotherapy, such as oxaliplatin and fluorouracil, work in different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. Oxaliplatin and fluorouracil may make tumor cells more sensitive to radiation therapy and may kill more tumor cells. Giving chemotherapy and radiation therapy before surgery may shrink the tumor so that it can be removed. PURPOSE: This phase II trial is studying how well giving oxaliplatin together with fluorouracil and radiation therapy works in treating patients who are undergoing surgery for stage II or stage III cancer of the esophagus or gastroesophageal junction.
Key facts
- Study ID
- NCT00086996
- Run by
- SWOG Cancer Research Network
- People needed
- 98
- Starts
- 2004-09-01
- Expected to finish
- 2011-08-01
- Last updated by the study team
- 2013-10-11
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Providence Cancer Center — Anchorage, Alaska, United States
- Highlands Oncology Group - Springdale — Bentonville, Arkansas, United States
- East Bay Radiation Oncology Center — Castro Valley, California, United States
- Eden Medical Center — Castro Valley, California, United States
- Valley Medical Oncology Consultants - Castro Valley — Castro Valley, California, United States
- Valley Medical Oncology — Fremont, California, United States
- USC/Norris Comprehensive Cancer Center and Hospital — Los Angeles, California, United States
- Highland General Hospital — Oakland, California, United States
- Alta Bates Summit Medical Center - Summit Campus — Oakland, California, United States
- Bay Area Breast Surgeons, Incorporated — Oakland, California, United States
- CCOP - Bay Area Tumor Institute — Oakland, California, United States
- Larry G Strieff MD Medical Corporation — Oakland, California, United States
- Tom K Lee, Incorporated — Oakland, California, United States
- Desert Regional Medical Center Comprehensive Cancer Center — Palm Springs, California, United States
- Valley Care Medical Center — Pleasanton, California, United States
- Valley Medical Oncology Consultants - Pleasanton — Pleasanton, California, United States
- University of California Davis Cancer Center — Sacramento, California, United States
- Doctors Medical Center - San Pablo Campus — San Pablo, California, United States
- Poudre Valley Hospital — Fort Collins, Colorado, United States
- Northeast Georgia Medical Center — Gainesville, Georgia, United States
- Curtis and Elizabeth Anderson Cancer Institute at Memorial Health University Medical Center — Savannah, Georgia, United States
- Saint Anthony's Hospital at Saint Anthony's Health Center — Alton, Illinois, United States
- Decatur Memorial Hospital Cancer Care Institute — Decatur, Illinois, United States
- Cardinal Bernardin Cancer Center at Loyola University Medical Center — Maywood, Illinois, United States
- Mobile Infirmary Medical Center — Mobile, Alabama, United States
Full record on ClinicalTrials.gov
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