Cetuximab and Carboplatin in Treating Patients With Recurrent Ovarian Epithelial Cancer or Primary Peritoneal Cancer

Completed · Phase 2

Conditions studied: Ovarian Cancer, Primary Peritoneal Cavity Cancer

In brief

RATIONALE: Monoclonal antibodies such as cetuximab can locate tumor cells and either kill them or deliver tumor-killing substances to them without harming normal cells. Drugs used in chemotherapy such as carboplatin work in different ways to stop tumor cells from dividing so they stop growing or die. Combining cetuximab with carboplatin may kill more tumor cells. PURPOSE: This phase II trial is studying how well giving cetuximab together with carboplatin works in treating patients with recurrent ovarian epithelial cancer or primary peritoneal cancer.

Key facts

Study ID

NCT00086892

Run by

Gynecologic Oncology Group

Starts

2004-06-01

Last updated by the study team

2014-02-14

Who can join

Age: 18 and older. Sex: female. Healthy volunteers: not accepted.

Where it is running

• CCOP - Western Regional, Arizona — Phoenix, Arizona, United States
• Jonsson Comprehensive Cancer Center at UCLA — Los Angeles, California, United States
• Women's Cancer Center - Los Gatos — Los Gatos, California, United States
• Chao Family Comprehensive Cancer Center at University of California Irvine Medical Center — Orange, California, United States
• University of Colorado Cancer Center at University of Colorado Health Sciences Center — Denver, Colorado, United States
• Yale Comprehensive Cancer Center at Yale University School of Medicine — New Haven, Connecticut, United States
• CCOP - Christiana Care Health Services — Newark, Delaware, United States
• Walter Reed Army Medical Center — Washington D.C., District of Columbia, United States
• H. Lee Moffitt Cancer Center and Research Institute at University of South Florida — Tampa, Florida, United States
• MBCCOP - Hawaii — Honolulu, Hawaii, United States
• Rush University Medical Center — Chicago, Illinois, United States
• MBCCOP - University of Illinois at Chicago — Chicago, Illinois, United States
• University of Chicago Cancer Research Center — Chicago, Illinois, United States
• CCOP - Central Illinois — Decatur, Illinois, United States
• CCOP - Evanston — Evanston, Illinois, United States
• Study site — Hinsdale, Illinois, United States
• CCOP - Carle Cancer Center — Urbana, Illinois, United States
• Indiana University Cancer Center — Indianapolis, Indiana, United States
• Saint Joseph Regional Medical Center — South Bend, Indiana, United States
• Holden Comprehensive Cancer Center at University of Iowa — Iowa City, Iowa, United States
• Markey Cancer Center at University of Kentucky Chandler Medical Center — Lexington, Kentucky, United States
• Tufts - New England Medical Center — Boston, Massachusetts, United States
• UMASS Memorial Cancer Center - University Campus — Worcester, Massachusetts, United States
• CCOP - Michigan Cancer Research Consortium — Ann Arbor, Michigan, United States
• Comprehensive Cancer Center at University of Alabama at Birmingham — Birmingham, Alabama, United States

Full record on ClinicalTrials.gov

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