Chemotherapy Combined With Radiation Therapy for Newly Diagnosed CNS AT/RT
Completed · Phase 2
Conditions studied: Central Nervous System Tumor, Pediatric
In brief
RATIONALE: Drugs used in chemotherapy work in different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. Giving more than one chemotherapy drug with radiation therapy may kill more tumor cells. PURPOSE: This phase II trial is studying how well giving intrathecal and systemic combination chemotherapy together with radiation therapy works in treating young patients with newly diagnosed central nervous system (CNS) atypical teratoid/rhabdoid tumors.
Key facts
- Study ID
- NCT00084838
- Run by
- Dana-Farber Cancer Institute
- People needed
- 25
- Starts
- 2003-02-01
- Expected to finish
- 2013-03-01
- Last updated by the study team
- 2015-12-24
Who can join
Age: any, up to 18. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Stanford Cancer Center — Stanford, California, United States
- Yale Cancer Center — New Haven, Connecticut, United States
- AFLAC Cancer Center and Blood Disorders Service of Children's Healthcare of Atlanta - Scottish Rite Campus — Atlanta, Georgia, United States
- Children's Memorial Hospital - Chicago — Chicago, Illinois, United States
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins — Baltimore, Maryland, United States
- Children's Hospital Boston — Boston, Massachusetts, United States
- Dana-Farber/Harvard Cancer Center at Dana Farber Cancer Institute — Boston, Massachusetts, United States
- Children's Hospitals and Clinics of Minnesota - Minneapolis — Minneapolis, Minnesota, United States
- Sunrise Hospital and Medical Center — Las Vegas, Nevada, United States
- Cleveland Clinic Taussig Cancer Center — Cleveland, Ohio, United States
- Children's Hospital of Philadelphia — Philadelphia, Pennsylvania, United States
- Simmons Comprehensive Cancer Center at University of Texas Southwestern Medical Center - Dallas — Dallas, Texas, United States
Full record on ClinicalTrials.gov
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