Prospective Evaluation of Anti-retroviral Combinations for Treatment Naive, HIV Infected Persons in Resource-limited Settings

Completed · Phase 4

Conditions studied: HIV Infections

In brief

This study compared 3 different three-drug combinations in HIV infected individuals starting their first HIV treatment regimens. Participants were recruited from resource-limited areas in Africa, Asia, South America, Haiti, and also from the United States. The study hypothesis was each of the once daily combinations (PI based, or NNRTI based) would not have inferior efficacy compared to the twice daily NNRTI based combination.

Key facts

Study ID

NCT00084136

Run by

Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections

People needed

1571

Starts

2005-05-01

Expected to finish

2010-05-01

Last updated by the study team

2018-10-10

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

Where it is running

• University of Southern California — Los Angeles, California, United States
• UCLA CARE Center CRS — Los Angeles, California, United States
• Harbor General/UCLA — Torrance, California, United States
• Univ. of Colorado Health Sciences Center, Denver — Denver, Colorado, United States
• Univ. of Hawaii at Manoa, Leahi Hosp. — Honolulu, Hawaii, United States
• Northwestern University — Chicago, Illinois, United States
• Rush-Presbyterian/St. Lukes (Chicago) — Chicago, Illinois, United States
• Cook County Hospital Core Center — Chicago, Illinois, United States
• University of Minnesota — Minneapolis, Minnesota, United States
• Washington University (St. Louis) — St Louis, Missouri, United States
• HIV Prevention & Treatment CRS — HVTN 722 West 168th Street MSPH Bldg., New York, United States
• Beth Israel Medical Center — New York, New York, United States
• Cornell CRS — New York, New York, United States
• NY Univ. HIV/AIDS CRS — New York, New York, United States
• Community Health Network, Inc. — Rochester, New York, United States
• Univ. of Rochester ACTG CRS — Rochester, New York, United States
• University of North Carolina — Chapel Hill, North Carolina, United States
• Wake County Health and Human Services Clinical Research Site — Chapel Hill, North Carolina, United States
• Duke University Medical Center — Durham, North Carolina, United States
• University of Cincinnati — Cincinnati, Ohio, United States
• The Ohio State Univ. AIDS CRS — Columbus, Ohio, United States
• Hosp. of the Univ. of Pennsylvania CRS — Philadelphia, Pennsylvania, United States
• Stanley Street Treatment and Resource — Providence, Rhode Island, United States
• The Miriam Hosp. ACTG CRS — Providence, Rhode Island, United States
• Vanderbilt Therapeutics CRS — Nashville, Tennessee, United States

Full record on ClinicalTrials.gov

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