Anastrozole Biphosphonate Study in Postmenopausal Women With Hormone-Receptor-Positive Early Breast Cancer
Completed · Phase 4
Conditions studied: Breast Cancer
In brief
The purpose of this study is to evaluate safety parameters of anastrozole with regard to its potential effects on postmenopausal bone loss and on lipid profiles. This trial is conducted to investigate the effects of risedronate on BMD and on bone metabolism in postmenopausal women using anastrozole as adjuvant therapy for hormone-receptor-positive early breast cancer and who are high or moderate risk of fragility fracture. It is also conducted to determine the effects of anastrozole on bone mineral density (BMD) and on bone metabolism in women at low risk of fragility fracture.
Key facts
- Study ID
- NCT00082277
- Run by
- AstraZeneca
- People needed
- 237
- Starts
- 2004-04-01
- Expected to finish
- 2007-10-01
- Last updated by the study team
- 2011-01-26
Who can join
Age: 55 and older. Sex: female. Healthy volunteers: not accepted.
You may qualify if…
- Women defined as Postmenopausal
- Histologically proven operable invasive breast cancer
- Hormone-receptor-positive breast cancer
You may not qualify if…
- Clinical evidence of metastatic disease
- Bilateral hip fractures or bilateral hip prosthesis
- Receiving or received in last 12 months hormonal therapy for breast cancer, bisphosphonate therapy, oestrogens
- Malabsorption syndrome
Where it is running
- Research Site — Palm Springs, California, United States
- Research Site — Jacksonville, Florida, United States
- Research Site — New Orleans, Louisiana, United States
- Research Site — New York, New York, United States
- Research Site — Raleigh, North Carolina, United States
- Research Site — Cleveland, Ohio, United States
- Research Site — Pittsburgh, Pennsylvania, United States
- Research Site — Houston, Texas, United States
- Research Site — Burnaby, Canada
- Research Site — Edmonton, Canada
- Research Site — Montreal, Canada
- Research Site — Québec, Canada
- Research Site — Vancouver, Canada
- Research Site — Bordeaux, France
- Research Site — Caen, France
- Research Site — Lyon, France
- Research Site — Saint-Cloud, France
- Research Site — Saint-Herblain, France
- Research Site — Athens, Greece
- Research Site — Irakleio, Greece
- Research Site — Goes, Netherlands
- Research Site — Ijssel, Netherlands
- Research Site — Nijmegen, Netherlands
- Research Site — The Hague, Netherlands
- Research Site — Bloemfontain, South Africa
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.