Study Evaluating Tigecycline Versus Imipenem/Cilastatin in Hospital-Acquired Pneumonia

Completed · Phase 3

Conditions studied: Bacterial Pneumonia

In brief

To compare the efficacy and safety of the tigecycline regimen with that of the imipenem/cilastatin regimen in subjects with nosocomial pneumonia.

Key facts

Study ID

NCT00080496

Run by

Wyeth is now a wholly owned subsidiary of Pfizer

People needed

430

Starts

2003-07-01

Expected to finish

2006-12-01

Last updated by the study team

2008-08-04

Who can join

Age: 18 and older, up to 70. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Male or female subjects over 18 years of age. Bulgaria Only: Male or female subjects over 18 years of age and under 70 years of age.
• Subjects known or suspected to have acute hospital-acquired pneumonia.

You may not qualify if…

• Presence of any of the following pulmonary conditions: cystic fibrosis; pulmonary malignancy (either primary or metastatic); known bronchial-obstructive or post obstructive pneumonia; pulmonary abscess; empyema; known or suspected active tuberculosis; bronchiectasis; sarcoidosis; known or suspected pulmonary infection caused by Pneumocystis carinii, mycobacteria, fungi, parasites, or viruses (Subjects with COPD are not excluded)
• Suspected or known Legionella infection
• Concurrent hemodialysis, hemofiltration, peritoneal dialysis, or plasmapheresis

Where it is running

• Study site — Phoenix, Arizona, United States
• Study site — Phoenix, Arizona, United States
• Study site — Scottsdale, Arizona, United States
• Study site — Scottsdale, Arizona, United States
• Study site — Martinez, California, United States
• Study site — Modesto, California, United States
• Study site — Modesto, California, United States
• Study site — National City, California, United States
• Study site — Bay Pines, Florida, United States
• Study site — Crystal River, Florida, United States
• Study site — Gainesville, Florida, United States
• Study site — Orlando, Florida, United States
• Study site — Atlanta, Georgia, United States
• Study site — Augusta, Georgia, United States
• Study site — Roswell, Georgia, United States
• Study site — Chicago, Illinois, United States
• Study site — Springfield, Illinois, United States
• Study site — Springfield, Illinois, United States
• Study site — New Orleans, Louisiana, United States
• Study site — Shreveport, Louisiana, United States
• Study site — Baltimore, Maryland, United States
• Study site — Columbia, Missouri, United States
• Study site — Omaha, Nebraska, United States
• Study site — Henderson, North Carolina, United States
• Study site — Cincinnati, Ohio, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.