Study of TLK286 (Telcyta) vs. Gefitinib in Locally Advanced or Metastatic Non-Small Cell Lung Cancer

Completed · Phase 3

Conditions studied: Non Small Cell Lung Carcinoma

In brief

The purpose of this study is to determine if TLK286(Telcyta) is more effective than gefitinib (Iressa) in the treatment of non-small cell lung cancer.

Key facts

Study ID

NCT00080340

Run by

Telik

People needed

520

Expected to finish

2005-05-01

Last updated by the study team

2008-01-15

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Clinical diagnosis of non-small cell lung cancer
• Non-small cell lung cancer that is not curable with surgery, radiation, or combined modality chemoradiation
• Failed two prior chemotherapy regimens which must have included platinum
• Measurable disease

You may not qualify if…

• Treatment with more than two prior chemotherapy regimens
• History of bone marrow transplantation or stem cell support
• Pregnant or lactating women
• Known history of prior gefitinib therapy
• Known history of prior TLK286 therapy

Where it is running

• Department of Veterans Affairs Medical Center — Birmingham, Alabama, United States
• University of Alabama at Birmingham — Birmingham, Alabama, United States
• University of Alabama at Birmingham — Birmingham, Alabama, United States
• Palo Verde Hematology Oncology — Glendale, Arizona, United States
• Little Rock Hematology Oncology Benton — Benton, Arkansas, United States
• Highlands Oncology Group — Bentonville, Arkansas, United States
• Highlands Oncology Group — Fayetteville, Arkansas, United States
• Heritage Physician Group, Oncology — Hot Springs, Arkansas, United States
• University of Arkansas for Medical Sciences — Little Rock, Arkansas, United States
• Highlands Oncology Group — Springdale, Arkansas, United States
• East Bay Medical Oncology/Hematology Medical Associates, Inc. — Antioch, California, United States
• East Valley Hematology Oncology Medical Group — Burbank, California, United States
• Providence Saint Joseph Medical Center — Burbank, California, United States
• Marilyn Norton, M. D. — Chula Vista, California, United States
• Rosalba Rodriquez, M. D. — Chula Vista, California, United States
• Bay Area Cancer Research Group — Concord, California, United States
• Wilshire Oncology Medical Group, Inc. — Glendora, California, United States
• Grossmont Hospital — La Mesa, California, United States
• Sharp Rees-Stealy — La Mesa, California, United States
• Wilshire Oncology Medical Group, Inc. — La Verne, California, United States
• North Valley Hematology Oncology Group — Mission Hills, California, United States
• Providence Holy Cross Medical Center — Mission Hills, California, United States
• Clinical Trials and Research Associates, Inc. — Montebello, California, United States
• Beverly Oncology & Imaging — Montebello, California, United States
• UAB CCC Clinical Studies Unit — Birmingham, Alabama, United States

Full record on ClinicalTrials.gov

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