Osteoarthritis Initiative (OAI): A Knee Health Study

Completed

Conditions studied: Osteoarthritis, Knee Osteoarthritis

In brief

Knee osteoarthritis (OA) is the most common cause of disability in adults. The "Osteoarthritis Initiative (OAI): A Knee Health Study" is a nationwide research study that will help researchers gather more information about the physical changes that occur prior to the onset of arthritis symptoms or before OA gets worse. The purpose of this study is to examine people who have knee OA or are at high risk for knee OA; information will be used to better understand how to prevent and treat knee OA.

Key facts

Study ID

NCT00080171

Run by

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

People needed

4796

Starts

2004-02-01

Expected to finish

2015-10-01

Last updated by the study team

2020-09-29

Who can join

Age: 45 and older, up to 79. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Must meet one of the following criteria:
• Overweight
• Previous knee injury or surgery
• Knee pain during the past year. Participants do not need to have current knee pain to take part in the study.
• Parent or sibling who had knee replacement

You may not qualify if…

• Rheumatoid arthritis
• Joint replacements in both knees
• Unable to walk without assistance
• Unable to undergo MRI of the knee

Where it is running

• University of Maryland — Baltimore, Maryland, United States
• Johns Hopkins University — Baltimore, Maryland, United States
• Ohio State University — Columbus, Ohio, United States
• University of Pittsburgh — Pittsburgh, Pennsylvania, United States
• Memorial Hospital of Rhode Island / Brown University — Pawtucket, Rhode Island, United States

Full record on ClinicalTrials.gov

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