Docetaxel and Cisplatin With or Without Dimesna in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer
Completed · Phase 2
Conditions studied: Anemia, Drug/Agent Toxicity by Tissue/Organ, Lung Cancer, Neutropenia
In brief
RATIONALE: Drugs used in chemotherapy, such as docetaxel and cisplatin, work in different ways to stop tumor cells from dividing so they stop growing or die. Chemoprotective drugs, such as dimesna, may help prevent or decrease the side effects (such as nerve, kidney, and inner ear damage) caused by chemotherapy. PURPOSE: This randomized phase II trial is studying giving docetaxel and cisplatin together with dimesna to see how well it works compared to giving docetaxel and cisplatin alone in treating patients with stage IIIB or stage IV non-small cell lung cancer.
Key facts
- Study ID
- NCT00077311
- Run by
- Alliance for Clinical Trials in Oncology
- People needed
- 160
- Starts
- 2004-08-01
- Expected to finish
- 2009-04-01
- Last updated by the study team
- 2016-06-30
Who can join
Age: 18 and older, up to 120. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Beebe Medical Center — Lewes, Delaware, United States
- CCOP - Christiana Care Health Services — Newark, Delaware, United States
- St. Francis Hospital — Wilmington, Delaware, United States
- St. Joseph Medical Center — Bloomington, Illinois, United States
- Graham Hospital — Canton, Illinois, United States
- Memorial Hospital — Carthage, Illinois, United States
- University of Illinois Cancer Center — Chicago, Illinois, United States
- Veterans Affairs Medical Center - Chicago Westside Hospital — Chicago, Illinois, United States
- University of Chicago Cancer Research Center — Chicago, Illinois, United States
- Louis A. Weiss Memorial Hospital — Chicago, Illinois, United States
- Eureka Community Hospital — Eureka, Illinois, United States
- Galesburg Clinic — Galesburg, Illinois, United States
- Galesburg Cottage Hospital — Galesburg, Illinois, United States
- Mason District Hospital — Havana, Illinois, United States
- Hopedale Medical Complex — Hopedale, Illinois, United States
- Kewanee Hospital — Kewanee, Illinois, United States
- McDonough District Hospital — Macomb, Illinois, United States
- BroMenn Regional Medical Center — Normal, Illinois, United States
- Community Cancer Center — Normal, Illinois, United States
- Community Hospital of Ottawa — Ottawa, Illinois, United States
- Oncology Hematology Associates of Central Illinois - Ottawa — Ottawa, Illinois, United States
- Cancer Treatment Center at Pekin Hospital — Pekin, Illinois, United States
- Proctor Hospital — Peoria, Illinois, United States
- CCOP - Illinois Oncology Research Association — Peoria, Illinois, United States
- El Camino Hospital — Mountain View, California, United States
Full record on ClinicalTrials.gov
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