Study of Brain Function During Cognitive Tasks
Completed
Conditions studied: Healthy
In brief
This study will use magnetic resonance imaging (MRI) to examine which areas of the brain are involved in performing certain cognitive tasks. MRI uses a strong magnetic field and radio waves to produce images of body tissues and organs that provide information about structure and function of tissues. Healthy normal volunteers between 21 and 40 years of age may be eligible for this study. Candidates must be native English speakers and must be right-handed. They must have no history of nervous system disease or psychiatric disorder. Candidates are screened with questionnaires and a neurological examination. Participants undergo functional MRI scanning. For this procedure, the subject lies on a stretcher that moves into the scanner - a metal cylinder surrounded by a strong magnetic field. During the scan, he or she is asked to make various decisions about whether words are related or not. Two words are presented visually, separated by a variable time delay. The subject reads both words, decides as quickly and accurately as possible whether the two words are related or not, and indicates the answer by pressing a button. The test takes about 2 hours. When it is completed, the subject completes a written questionnaire concerning his or her experience in the scanner. ...
Key facts
- Study ID
- NCT00076739
- Run by
- National Institute of Neurological Disorders and Stroke (NINDS)
- People needed
- 452
- Starts
- 2004-02-02
- Expected to finish
- 2011-12-12
- Last updated by the study team
- 2017-07-02
Who can join
Age: 21 and older, up to 40. Sex: any. Healthy volunteers: accepted.
You may not qualify if…
- Non-native English speakers and non-right handers will be excluded as mentioned above, as will non-neurologically normal volunteers.
- Subjects younger than 21 and older than 40 will be excluded.
- A pregnancy test will be employed with all women of childbearing age. The results must be negative in order to proceed with the MRI.
- Subjects with any of the following: aneurysm clip; implanted neural stimulator; implanted cardiac pacemaker or auto-defibrillator; cochlear implant; ocular foreign body, e.g. metal shavings; permanent eyeliner; insulin pump; or irremovable body piercing will be excluded from the study due to the possible dangerous effects of the magnet upon metal objects in the body.
- Subjects taking central nervous system active medications will be excluded.
Where it is running
- National Institutes of Health Clinical Center, 9000 Rockville Pike — Bethesda, Maryland, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.