Octreotide in Preventing or Reducing Diarrhea in Patients Receiving Chemoradiotherapy for Anal or Rectal Cancer

Completed · Phase 3 · Has a placebo group

Conditions studied: Anal Cancer, Colorectal Cancer, Drug/Agent Toxicity by Tissue/Organ, Radiation Enteritis

In brief

RATIONALE: Octreotide may be effective in preventing or controlling diarrhea in patients who are undergoing chemoradiotherapy for anal or rectal cancer. It is not yet known whether octreotide is effective in treating diarrhea. PURPOSE: This randomized phase III trial is studying octreotide in preventing or reducing diarrhea in patients who are undergoing chemoradiotherapy for anal or rectal cancer.

Key facts

Study ID

NCT00075868

Run by

Radiation Therapy Oncology Group

People needed

233

Starts

2003-12-01

Last updated by the study team

2015-11-17

Who can join

Age: 18 and older, up to 120. Sex: any. Healthy volunteers: not accepted.

Where it is running

• Foundation for Cancer Research and Education — Phoenix, Arizona, United States
• Enloe Cancer Center at Enloe Medical Center — Chico, California, United States
• Saint Agnes Medical Center — Fresno, California, United States
• California Cancer Center - Woodward Park Office — Fresno, California, United States
• Sutter Health Western Division Cancer Research Group — Greenbrae, California, United States
• Cancer Care Consultants Medical Associates at Daniel Freeman Memorial Hospital — Inglewood, California, United States
• Leavey Cancer Center at Northridge Hospital Medical Center — Northridge, California, United States
• CCOP - Bay Area Tumor Institute — Oakland, California, United States
• Pomona Valley Hospital Medical Center — Pomona, California, United States
• Radiological Associates of Sacramento Medical Group, Incorporated — Sacramento, California, United States
• University of California Davis Cancer Center — Sacramento, California, United States
• Torrance Memorial Medical Center — Torrance, California, United States
• Memorial Hospital Cancer Center — Colorado Springs, Colorado, United States
• St. Mary's Regional Cancer Center at St. Mary's Hospital and Medical Center — Grand Junction, Colorado, United States
• Sibley Memorial Hospital — Washington D.C., District of Columbia, United States
• Michael & Dianne Bienes Comprehensive Cancer Center at Holy Cross Hospital — Fort Lauderdale, Florida, United States
• University of Florida Shands Cancer Center — Gainesville, Florida, United States
• Memorial Cancer Institute at Memorial Regional Hospital — Hollywood, Florida, United States
• Baptist Cancer Institute - Jacksonville — Jacksonville, Florida, United States
• Ella Milbank Foshay Cancer Center at Jupiter Medical Center — Jupiter, Florida, United States
• University of Miami Sylvester Comprehensive Cancer Center — Miami, Florida, United States
• Baptist-South Miami Regional Cancer Program — Miami, Florida, United States
• CCOP - Mount Sinai Medical Center — Miami Beach, Florida, United States
• H. Lee Moffitt Cancer Center and Research Institute at University of South Florida — Tampa, Florida, United States
• Mobile Infirmary Medical Center — Mobile, Alabama, United States

Full record on ClinicalTrials.gov

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