The Research Registry for Neonatal Lupus

Completed

Conditions studied: Neonatal Lupus, Systemic Lupus Erythematosus, Sjogren's Syndrome, Congenital Heart Block

In brief

Women with lupus and other related disorders produce certain antibodies in the blood. Some women have these antibodies even if they have not yet developed symptoms of lupus or Sjogren's syndrome. When these women become pregnant, they may pass the antibodies to their infants. The infants may then develop a disease called neonatal lupus. The symptoms of neonatal lupus include an abnormally slow heart beat (heart block) and a skin rash. This registry collects information on women and infants affected by neonatal lupus as well as other family members who may be healthy.

Key facts

Study ID

NCT00074373

Run by

NYU Langone Health

People needed

100

Starts

2010-05-27

Expected to finish

2016-06-01

Last updated by the study team

2023-08-03

Who can join

Age: any. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Mother with antibodies to SSA/Ro, SSB/La, or ribonucleoproteins (RNP) OR Child of mother with such antibodies who has neonatal lupus (congenital heart block, transient skin rash, and/or hepatic or hematologic manifestations) OR Father of neonatal lupus-affected child OR Maternal grandparents of neonatal lupus-affected child OR Maternal aunts and uncles of neonatal lupus-affected OR Unaffected siblings of neonatal lupus-affected child

Where it is running

• Jill P. Buyon, MD — New York, New York, United States

Full record on ClinicalTrials.gov

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