Pentostatin in Treating Patients With Refractory Chronic Graft-Versus-Host Disease
Completed · Phase 2
Conditions studied: Graft Versus Host Disease
In brief
RATIONALE: Pentostatin may be effective in treating chronic graft-versus-host disease by stopping the immune system from rejecting donor stem cells or donor white blood cells. PURPOSE: This phase II trial is studying how well pentostatin works in treating patients with chronic graft-versus-host disease that is refractory (not responsive) to treatment with steroids.
Key facts
- Study ID
- NCT00074035
- Run by
- Alliance for Clinical Trials in Oncology
- People needed
- 39
- Starts
- 2003-12-01
- Expected to finish
- 2014-11-01
- Last updated by the study team
- 2021-11-03
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Tunnell Cancer Center at Beebe Medical Center — Lewes, Delaware, United States
- CCOP - Christiana Care Health Services — Newark, Delaware, United States
- University of Illinois Cancer Center — Chicago, Illinois, United States
- University of Chicago Cancer Research Center — Chicago, Illinois, United States
- Greenebaum Cancer Center at University of Maryland Medical Center — Baltimore, Maryland, United States
- Union Hospital Cancer Program at Union Hospital — Elkton, Maryland, United States
- Mayo Clinic Cancer Center — Rochester, Minnesota, United States
- Cancer Institute of New Jersey at Cooper - Voorhees — Voorhees Township, New Jersey, United States
- New York Weill Cornell Cancer Center at Cornell University — New York, New York, United States
- Duke Comprehensive Cancer Center — Durham, North Carolina, United States
- Wake Forest University Comprehensive Cancer Center — Winston-Salem, North Carolina, United States
- Arthur G. James Cancer Hospital and Solove Research Institute at Ohio State University Medical Center — Columbus, Ohio, United States
- Abramson Cancer Center of the University of Pennsylvania — Philadelphia, Pennsylvania, United States
- Fox Chase Cancer Center - Philadelphia — Philadelphia, Pennsylvania, United States
- Western Pennsylvania Cancer Institute at Western Pennsylvania Hospital — Pittsburgh, Pennsylvania, United States
- Virginia Commonwealth University Massey Cancer Center — Richmond, Virginia, United States
Full record on ClinicalTrials.gov
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