Treating Behavioral Disturbances in Individuals With Dementia
Completed · Phase 2
Conditions studied: Dementia
In brief
This study will compare the safety and effectiveness two medications, citalopram (Celexa®) and risperidone (Risperdal®).
Key facts
- Study ID
- NCT00073658
- Run by
- University of Pittsburgh
- People needed
- 137
- Starts
- 2000-01-01
- Expected to finish
- 2005-06-01
- Last updated by the study team
- 2014-03-10
Who can join
Age: 50 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Diagnosis of Alzheimer's type dementia and/or meet criteria for probable or possible Alzheimer's disease
- Inpatient admittance to Western Psychiatric Institute and Clinic
- Written informed consent from participant's legally authorized representative with the participant's assent
- Psychosis or behavioral problems severe enough to be a danger to the participant's health, well-being, or safety
- Score of 3 to 6 (moderate to severe) on at least one of the Neurobehavioral Rating Scale (NBRS) agitation or psychosis items
- Ability to participate in study evaluation and ingest oral medication
You may not qualify if…
- Diagnosis of an unstable medical illness within the last 12 months
- Kidney or liver dysfunction
- Diagnosis of delirium, substance-induced persisting dementia, or vascular dementia
- Score of 12 or higher on the Cornell Scale for Depression in Dementia, and a score greater than 3 on the depression item of the NBRS
- Diagnosis of Parkinson's disease or any neurological illness which may affect cognitive function
- History of schizophrenia, schizoaffective disorder, delusional disorder, psychotic disorders not otherwise specified, or bipolar affective disorder
- Alcohol or substance abuse or dependence
- Receiving monoamine oxidase inhibitors within 15 days of study
- Display behaviors which could endanger the participant's life or the lives of others
- Received fluoxetine within 4 weeks of screening
Where it is running
- University of Pittsburgh Medical Center/Western Psychiatric Institute and Clinic — Pittsburgh, Pennsylvania, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.