Factors Affecting Adherence to Anti-HIV Drug Regimens in Children and Adolescents

Completed

Conditions studied: HIV Infections

In brief

Taking anti-HIV medication consistently and properly is a critical issue for patients with HIV. Drug regimens are complex; when regimens are not taken properly, HIV can become resistant to the drugs. Taking anti-HIV medication properly leads to improved health. Children and adolescents with HIV face unique challenges to taking HIV medication properly. This study will look at the relationship between how children cope with the responsibility for taking medication and the child's language, memory, attention, behavior, and academic skills. This study is open to children and adolescents who are currently enrolled in the PACTG 219C study (Long-Term Effects of HIV Exposure and Infection in Children).

Key facts

Study ID

NCT00073424

Run by

National Institute of Allergy and Infectious Diseases (NIAID)

People needed

200

Starts

2004-01-01

Expected to finish

2006-10-01

Last updated by the study team

2013-06-03

Who can join

Age: 8 and older, up to 19. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• HIV-1 perinatal infection
• Already enrolled and in active follow-up in PACTG 219C
• Can communicate in English or Spanish
• On antiretroviral medication regimen at the time of enrollment, regardless of compliance with regimen, with no planned treatment interruptions

You may not qualify if…

• Acquired HIV via routes other than perinatal transmission or source of HIV infection is unknown
• HIV-2 infection

Where it is running

• UAB, Dept. of Ped., Div. of Infectious Diseases — Birmingham, Alabama, United States
• Phoenix Children's Hosp. — Phoenix, Arizona, United States
• Long Beach Memorial Med. Ctr., Miller Children's Hosp. — Long Beach, California, United States
• Usc La Nichd Crs — Los Angeles, California, United States
• Children's Hosp. & Research Ctr. Oakland, Ped. Clinical Research Ctr. & Research Lab. — Oakland, California, United States
• UCSD Mother-Child-Adolescent Program CRS — San Diego, California, United States
• UCSF Pediatric AIDS CRS — San Francisco, California, United States
• Univ. of Colorado Denver NICHD CRS — Denver, Colorado, United States
• Yale Univ. School of Medicine - Dept. of Peds., Div. of Infectious Disease — New Haven, Connecticut, United States
• Children's National Med. Ctr., ACTU — Washington D.C., District of Columbia, United States
• Howard Univ. Washington DC NICHD CRS — Washington D.C., District of Columbia, United States
• South Florida CDTC Ft Lauderdale NICHD CRS — Fort Lauderdale, Florida, United States
• Univ. of Miami Ped. Perinatal HIV/AIDS CRS — Miami, Florida, United States
• Med. College of Georgia School of Medicine, Dept. of Peds., Div. of Infectious Diseases — Augusta, Georgia, United States
• Chicago Children's CRS — Chicago, Illinois, United States
• Tulane/LSU Maternal/Child CRS — New Orleans, Louisiana, United States
• Univ. of Maryland Med. Ctr., Div. of Ped. Immunology & Rheumatology — Baltimore, Maryland, United States
• Johns Hopkins Hosp. & Health System - Dept. of Peds., Div. of Infectious Diseases — Baltimore, Maryland, United States
• HMS - Children's Hosp. Boston, Div. of Infectious Diseases — Boston, Massachusetts, United States
• Baystate Medical Center, Springfield — Springfield, Massachusetts, United States
• NJ Med. School CRS — Newark, New Jersey, United States
• SUNY Downstate Med. Ctr., Children's Hosp. at Downstate NICHD CRS — Brooklyn, New York, United States
• Nyu Ny Nichd Crs — New York, New York, United States
• Harlem Hosp. Ctr. NY NICHD CRS — New York, New York, United States
• SUNY Stony Brook NICHD CRS — Stony Brook, New York, United States

Full record on ClinicalTrials.gov

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