A Study of ABT-751 in Patients With Non-Small Cell Lung Cancer

Completed · Phase 2

Conditions studied: Non-Small Cell Lung Cancer

In brief

The purpose of the study is to determine if ABT-751 will decrease tumors, and determine how long the tumor shrinkage can be maintained in patients with non-small cell lung cancer. Patients will receive ABT-751 by mouth daily for 21 days. Patients will be off drug for 7 days before starting the next cycle of drug.

Key facts

Study ID

NCT00073151

Run by

Abbott

People needed

30

Starts

2003-09-01

Expected to finish

2006-01-01

Last updated by the study team

2007-11-29

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Stage IIIB or IV non-small cell lung cancer.
• Recurrent tumor following treatment with paclitaxel or docetaxel.
• Able to tolerate normal activities of daily living.
• Adequate bone marrow, kidney and liver function.

You may not qualify if…

• Pregnant or breast feeding.
• Anti-tumor therapy within 4 weeks of the start of ABT-751 administration.
• CNS metastasis.

Where it is running

• Oncology Hematology Group of South Florida — Miami, Florida, United States
• Florida Cancer Institute — New Port Richey, Florida, United States
• University of Chicago Medical Center — Chicago, Illinois, United States
• University of Maryland Greenbaum Cancer Center — Baltimore, Maryland, United States
• Oncology & Hematology Associates of Kansas City, PA — Kansas City, Missouri, United States
• Washington University School of Medicine — St Louis, Missouri, United States
• Albany Regional Cancer Center — Albany, New York, United States
• Raleigh Hematology Oncology — Cary, North Carolina, United States
• Dayton Oncology and Hematology — Kettering, Ohio, United States
• Cancer Care Associates — Oklahoma City, Oklahoma, United States
• Cancer Centers of the Carolinas — Greenville, South Carolina, United States
• West Cancer Clinic — Memphis, Tennessee, United States
• Texas Oncology — Dallas, Texas, United States
• Texas Oncology — Fort Worth, Texas, United States
• Cancer Care Northwest — Spokane, Washington, United States
• Northwest Cancer Specialists — Vancouver, Washington, United States
• University of Wisconsin Comprehensive Cancer Center — Madison, Wisconsin, United States

Full record on ClinicalTrials.gov

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