Interferon Alfa-2b With or Without Bevacizumab in Treating Patients With Advanced Renal Cell Carcinoma (Kidney Cancer)
Completed · Phase 3
Conditions studied: Kidney Cancer
In brief
RATIONALE: Biological therapies, such as interferon alfa-2b, may interfere with the growth of tumor cells. Bevacizumab may stop the growth of tumor cells by stopping blood flow to the tumor. It is not yet known whether interferon alfa-2b is more effective with or without bevacizumab in treating advanced renal cell carcinoma (kidney cancer). PURPOSE: This randomized phase III trial is studying interferon alfa-2b and bevacizumab to see how well they work compared to interferon alfa-2b alone in treating patients with advanced renal cell carcinoma.
Key facts
- Study ID
- NCT00072046
- Run by
- Alliance for Clinical Trials in Oncology
- People needed
- 732
- Starts
- 2003-10-01
- Expected to finish
- 2012-11-01
- Last updated by the study team
- 2016-07-06
Who can join
Age: 18 and older, up to 120. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Huntsville Hospital — Huntsville, Alabama, United States
- CCOP - Mayo Clinic Scottsdale Oncology Program — Scottsdale, Arizona, United States
- Hembree Mercy Cancer Center at St. Edward Mercy Medical Center — Fort Smith, Arkansas, United States
- Arroyo Grande Community Hospital — Arroyo Grande, California, United States
- City of Hope Comprehensive Cancer Center — Duarte, California, United States
- Kaiser Permanente - Fremont — Fremont, California, United States
- Kaiser Permanente Medical Center - Hayward — Hayward, California, United States
- Providence Holy Cross Cancer Center — Mission Hills, California, United States
- Kaiser Permanente Medical Center - Oakland — Oakland, California, United States
- St. Joseph Hospital Regional Cancer Center - Orange — Orange, California, United States
- Kaiser Permanente Medical Center - Redwood City — Redwood City, California, United States
- Kaiser Permanente Medical Center - Richmond — Richmond, California, United States
- Kaiser Permanente Medical Center - Roseville — Roseville, California, United States
- South Sacramento Kaiser-Permanente Medical Center — Sacramento, California, United States
- Kaiser Permanente Medical Center - Sacramento — Sacramento, California, United States
- Rebecca and John Moores UCSD Cancer Center — San Diego, California, United States
- Kaiser Permanente Medical Office -Vandever Medical Office — San Diego, California, United States
- Naval Medical Center - San Diego — San Diego, California, United States
- Veterans Affairs Medical Center - San Diego — San Diego, California, United States
- San Francisco General Hospital Medical Center — San Francisco, California, United States
- Kaiser Permanente Medical Center - San Francisco Geary Campus — San Francisco, California, United States
- UCSF Comprehensive Cancer Center — San Francisco, California, United States
- Veterans Affairs Medical Center - San Francisco — San Francisco, California, United States
- Kaiser Permanente Medical Center - Santa Teresa — San Jose, California, United States
- Comprehensive Cancer Center at University of Alabama at Birmingham — Birmingham, Alabama, United States
Full record on ClinicalTrials.gov
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