Vaccine Therapy and Sargramostim After Rituximab in Treating Patients With Refractory or Progressive Non-Hodgkin's Lymphoma
Completed · Phase 2
Conditions studied: Lymphoma
In brief
RATIONALE: Monoclonal antibodies such as rituximab can locate cancer cells and either kill them or deliver cancer-killing substances to them without harming normal cells. Vaccines made from a person's cancer cells may make the body build an immune response to kill cancer cells. Colony-stimulating factors such as sargramostim may increase the number of immune cells found in bone marrow or peripheral blood. PURPOSE: Phase II trial to study the effectiveness of rituximab followed by vaccine therapy and sargramostim in treating patients who have refractory or progressive non-Hodgkin's lymphoma.
Key facts
- Study ID
- NCT00071955
- Run by
- Genitope Corporation
- Starts
- 2003-03-01
- Expected to finish
- 2009-01-01
- Last updated by the study team
- 2013-12-19
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Stanford Cancer Center at Stanford University Medical Center — Stanford, California, United States
- Rush Cancer Institute at Rush University Medical Center — Chicago, Illinois, United States
- Indiana University Cancer Center — Indianapolis, Indiana, United States
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins — Baltimore, Maryland, United States
- Dana-Farber/Harvard Cancer Center at Dana Farber Cancer Institute — Boston, Massachusetts, United States
- Siteman Cancer Center at Barnes-Jewish Hospital — St Louis, Missouri, United States
- UNMC Eppley Cancer Center at the University of Nebraska Medical Center — Omaha, Nebraska, United States
- New York Weill Cornell Cancer Center at Cornell University — New York, New York, United States
- Cancer Institute at Oregon Health and Science University — Portland, Oregon, United States
- Cross Cancer Institute at University of Alberta — Edmonton, Alberta, Canada
- Toronto Sunnybrook Regional Cancer Centre at Sunnybrook and Women's College Health Sciences Centre — Toronto, Ontario, Canada
Full record on ClinicalTrials.gov
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