Ginkgo Biloba to Improve Short-Term Memory Losses Associated With Electroconvulsive Therapy (ECT)
Stopped early · Phase 1/Phase 2 · Has a placebo group
Conditions studied: Memory, Short-Term
In brief
Electroconvulsive therapy (ECT) is an effective treatment for severe or medication-resistant depression and other psychiatric disorders. A common side effect of ECT is problems with short-term memory during treatment. This study will test whether taking ginkgo biloba (GB) prior to and during the course of ECT will lessen the effects of ECT on short-term memory.
Key facts
- Study ID
- NCT00070954
- Run by
- Medical University of South Carolina
- People needed
- 50
- Starts
- 2003-02-01
- Expected to finish
- 2005-03-01
- Last updated by the study team
- 2018-07-18
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- DSM-IV diagnosis of major depressive episode, unipolar or bipolar, without psychotic features
- Receiving ECT for depression
- Able to complete detailed neuropsychological testing
You may not qualify if…
- Psychotic symptoms
- Lifetime history of schizophrenia, schizoaffective disorder, or mental retardation
- Diagnosis of anxiety disorder, obsessive-compulsive disorder, or eating disorder within 1 year of study entry
- Delirium, dementia, or amnestic disorder
- Any active general medical condition or central nervous system disease which could affect cognition or response to treatment
- Diagnosis of active substance abuse or dependence within 6 months of study entry
- ECT within 6 months of study entry
- Known or suspected coagulation disorder
- Anticoagulation or antiplatelet medications, including warfarin, aspirin, clopidogrel, and ticlopidine
- Thiazide diuretics, selective serotonin reuptake inhibitors, trazodone, antipsychotic medications, herbal medications, or other nutritional supplements
- Pregnancy
Where it is running
- UMDNJ - NJ Medical School — Newark, New Jersey, United States
Full record on ClinicalTrials.gov
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