Prenatal Screening For Smith-Lemli-Opitz Syndrome

Completed

Conditions studied: Smith-Lemli-Opitz Syndrome, Pregnancy

In brief

Smith-Lemli-Opitz Syndrome (SLOS) is a genetic condition that causes mental retardation and other birth defects. This study will evaluate a new prenatal screening test for SLOS.

Key facts

Study ID

NCT00070850

Run by

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

People needed

1800

Starts

2001-04-01

Expected to finish

2005-07-01

Last updated by the study team

2007-07-02

Who can join

Age: any. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• Pregnant, second trimester
• Singleton pregnancy
• Positive second trimester maternal serum screen for Smith-Lemli-Opitz Syndrome (using the Foundation for Blood Research screening algorithm )

You may not qualify if…

• Gestational age at time of serum collection outside the range accepted for Down Syndrome screening
• Not pregnant
• Twin/multiple pregnancy
• Sample/clerical/assay error
• Physician not participating in study

Where it is running

• Foundation for Blood Research — Scarborough, Maine, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.