S0221 Adjuvant Doxorubicin, Cyclophosphamide, and Paclitaxel in Treating Patients With Breast Cancer
Running, not enrolling · Phase 3
Conditions studied: Breast Cancer
In brief
RATIONALE: Drugs used in chemotherapy, such as doxorubicin, cyclophosphamide, and paclitaxel, use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug and giving them after surgery may kill any remaining tumor cells. It is not yet known which combination chemotherapy regimen is more effective in treating resected breast cancer. PURPOSE: This randomized phase III trial is comparing 2 different regimens of combination chemotherapy to see how well they work in treating patients who have undergone surgery for stage I, stage II, or stage III breast cancer.
Key facts
- Study ID
- NCT00070564
- Run by
- SWOG Cancer Research Network
- People needed
- 3294
- Starts
- 2003-11-01
- Expected to finish
- 2027-01-01
- Last updated by the study team
- 2025-07-31
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- UAB Comprehensive Cancer Center — Birmingham, Alabama, United States
- Providence Cancer Center at Providence Hospital — Mobile, Alabama, United States
- Providence Cancer Center — Anchorage, Alaska, United States
- Mayo Clinic Scottsdale — Scottsdale, Arizona, United States
- Arizona Cancer Center at University of Arizona Health Sciences Center — Tucson, Arizona, United States
- Hembree Mercy Cancer Center at St. Edward Mercy Medical Center — Fort Smith, Arkansas, United States
- Arkansas Cancer Research Center at University of Arkansas for Medical Sciences — Little Rock, Arkansas, United States
- Alta Bates Summit Comprehensive Cancer Center — Berkeley, California, United States
- Peninsula Medical Center — Burlingame, California, United States
- East Bay Radiation Oncology Center — Castro Valley, California, United States
- Valley Medical Oncology Consultants - Castro Valley — Castro Valley, California, United States
- Valley Medical Oncology — Fremont, California, United States
- California Cancer Center - Woodward Park Office — Fresno, California, United States
- Todd Cancer Institute at Long Beach Memorial Medical Center — Long Beach, California, United States
- USC/Norris Comprehensive Cancer Center and Hospital — Los Angeles, California, United States
- Contra Costa Regional Medical Center — Martinez, California, United States
- Tibotec Therapeutics - Division of Ortho Biotech Products, LP — Marysville, California, United States
- Memorial Medical Center — Modesto, California, United States
- El Camino Hospital Cancer Center — Mountain View, California, United States
- Sutter Health - Western Division Cancer Research Group — Novato, California, United States
- Highland General Hospital — Oakland, California, United States
- Alta Bates Summit Medical Center - Summit Campus — Oakland, California, United States
- Bay Area Breast Surgeons, Incorporated — Oakland, California, United States
- CCOP - Bay Area Tumor Institute — Oakland, California, United States
- Regional Medical Center — Anniston, Alabama, United States
Full record on ClinicalTrials.gov
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