S0313 Cyclophosphamide, Doxorubicin, Vincristine, Prednisone, and Radiation Therapy Followed By Rituximab and Yttrium Y 90 Ibritumomab Tiuxetan in Treating Patients With Stage I or Stage II Non-Hodgkin's Lymphoma
Completed · Phase 2
Conditions studied: Lymphoma
In brief
RATIONALE: Drugs used in chemotherapy, such as cyclophosphamide, doxorubicin, vincristine, and prednisone, use different ways to stop cancer cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage cancer cells. Monoclonal antibodies, such as rituximab and yttrium Y 90 ibritumomab tiuxetan, can locate cancer cells and either kill them or deliver radioactive cancer-killing substances to them without harming normal cells. Combining chemotherapy with radiation therapy and monoclonal antibody therapy may kill more cancer cells. PURPOSE: This phase II trial is studying how well giving combination chemotherapy together with radiation therapy and monoclonal antibody therapy works in treating patients with stage I or stage II non-Hodgkin's lymphoma.
Key facts
- Study ID
- NCT00070018
- Run by
- SWOG Cancer Research Network
- People needed
- 46
- Starts
- 2004-02-01
- Expected to finish
- 2015-01-08
- Last updated by the study team
- 2022-01-11
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Alaska Regional Hospital Cancer Center — Anchorage, Alaska, United States
- Providence Cancer Center — Anchorage, Alaska, United States
- Providence Saint Joseph Medical Center - Burbank — Burbank, California, United States
- Mountain States Tumor Institute at St. Luke's Regional Medical Center — Boise, Idaho, United States
- Decatur Memorial Hospital Cancer Care Institute — Decatur, Illinois, United States
- Cardinal Bernardin Cancer Center at Loyola University Medical Center — Maywood, Illinois, United States
- Edward Hospital Cancer Center — Naperville, Illinois, United States
- Regional Cancer Center at Memorial Medical Center — Springfield, Illinois, United States
- Cancer Center of Kansas, PA - Chanute — Chanute, Kansas, United States
- Cancer Center of Kansas, PA - Dodge City — Dodge City, Kansas, United States
- Cancer Center of Kansas, PA - El Dorado — El Dorado, Kansas, United States
- Cancer Center of Kansas-Independence — Independence, Kansas, United States
- Cancer Center of Kansas, PA - Kingman — Kingman, Kansas, United States
- Southwest Medical Center — Liberal, Kansas, United States
- Cancer Center of Kansas, PA - Newton — Newton, Kansas, United States
- Cancer Center of Kansas, PA - Parsons — Parsons, Kansas, United States
- Cancer Center of Kansas, PA - Pratt — Pratt, Kansas, United States
- Cancer Center of Kansas, PA - Salina — Salina, Kansas, United States
- Cotton-O'Neil Cancer Center — Topeka, Kansas, United States
- Cancer Center of Kansas, PA - Wellington — Wellington, Kansas, United States
- Associates in Womens Health, PA - North Review — Wichita, Kansas, United States
- Cancer Center of Kansas, PA - Medical Arts Tower — Wichita, Kansas, United States
- Cancer Center of Kansas, PA - Wichita — Wichita, Kansas, United States
- CCOP - Wichita — Wichita, Kansas, United States
- Via Christi Cancer Center at Via Christi Regional Medical Center — Wichita, Kansas, United States
Full record on ClinicalTrials.gov
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