Combination Chemotherapy Followed By Chemoradiotherapy, With or Without Surgery, in Treating Patients With Resectable Locally Advanced Cancer of the Esophagus or Gastroesophageal Junction
Completed · Phase 2
Conditions studied: Esophageal Cancer
In brief
RATIONALE: Drugs used in chemotherapy such as paclitaxel, fluorouracil, and cisplatin use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. Combining chemotherapy with radiation therapy may kill more tumor cells PURPOSE: This phase II trial is studying how well combination chemotherapy followed by chemoradiotherapy, with or without surgery, works in treating patients with resectable locally advanced cancer of the esophagus or gastroesophageal junction.
Key facts
- Study ID
- NCT00069953
- Run by
- Radiation Therapy Oncology Group
- People needed
- 43
- Starts
- 2003-09-01
- Expected to finish
- 2016-12-01
- Last updated by the study team
- 2017-02-17
Who can join
Age: 18 and older, up to 120. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Saint Rose Hospital — Hayward, California, United States
- Providence Holy Cross Cancer Center — Mission Hills, California, United States
- CCOP - Bay Area Tumor Institute — Oakland, California, United States
- Summit Medical Center — Oakland, California, United States
- Valley Care Medical Center — Pleasanton, California, United States
- J.C. Robinson, M.D. Regional Cancer Center — San Pablo, California, United States
- University of Colorado Cancer Center at University of Colorado Health Sciences Center — Aurora, Colorado, United States
- Hospital of Saint Raphael — New Haven, Connecticut, United States
- Baptist-South Miami Regional Cancer Program — Miami, Florida, United States
- Gulf Coast Cancer Treatment Center — Panama City, Florida, United States
- Curtis & Elizabeth Anderson Cancer Institute at Memorial Health University Medical Center — Savannah, Georgia, United States
- Mount Sinai Hospital Medical Center — Chicago, Illinois, United States
- St. Francis Hospital and Health Centers - Beech Grove Campus — Beech Grove, Indiana, United States
- Wendt Regional Cancer Center at Finley Hospital — Dubuque, Iowa, United States
- Ochsner Clinic of Baton Rouge — Baton Rouge, Louisiana, United States
- CCOP - Ochsner — New Orleans, Louisiana, United States
- St. Joseph Mercy Cancer Center at St. Joseph Mercy Hospital — Ann Arbor, Michigan, United States
- CCOP - Michigan Cancer Research Consortium — Ann Arbor, Michigan, United States
- Oakwood Cancer Center at Oakwood Hospital and Medical Center — Dearborn, Michigan, United States
- Green Bay Oncology, Limited - Escanaba — Escanaba, Michigan, United States
- Genesys Hurley Cancer Institute — Flint, Michigan, United States
- Van Elslander Cancer Center at St. John Hospital and Medical Center — Grosse Pointe Woods, Michigan, United States
- Green Bay Oncology, Limited - Iron Mountain — Iron Mountain, Michigan, United States
- Foote Hospital — Jackson, Michigan, United States
- Providence Saint Joseph Medical Center - Burbank — Burbank, California, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.