Diet/Growth Factor Mechanisms of Gut Adaptation
Completed · Phase 2
Conditions studied: Short Bowel Syndrome
In brief
This is a double-blind randomized controlled study on the clinical and metabolic effects and underlying gut mucosal mechanisms of modified diet, with or without recombinant human growth hormone, in adults with severe short bowel syndrome dependent upon parenteral nutrition. Clinical endpoints include ability to wean patients from parenteral feeding, metabolic endpoints include gut nutrient absorptive function and molecular endpoints include expression of growth factors and nutrient transporters in small bowel and colonic mucosa. The 6-month study is performed, in part, in the General Clinical Research Center for inpatient stays and outpatient visits.
Key facts
- Study ID
- NCT00067860
- Run by
- Emory University
- People needed
- 27
- Starts
- 1996-10-01
- Expected to finish
- 2006-12-01
- Last updated by the study team
- 2016-05-16
Who can join
Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Emory University School of Medicine — Atlanta, Georgia, United States
Full record on ClinicalTrials.gov
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