Metabolic Abnormalities in HIV Infected and Uninfected Young Women

Completed

Conditions studied: HIV Infections, Hypercholesterolemia, Glucose Intolerance

In brief

Though anti-HIV drugs can dramatically improve the health of people with HIV, some people taking these drugs develop serious long term effects in their metabolism. These effects include problems with bones, increased levels of blood sugar and lipids, and changes in body fat distribution. The purpose of this study is to see how many young women are experiencing these problems and how severe the problems are. This kind of study is the first step in determining how best to treat these problems.

Key facts

Study ID

NCT00067587

Run by

University of North Carolina, Chapel Hill

People needed

300

Starts

2003-07-01

Expected to finish

2005-06-01

Last updated by the study team

2017-03-01

Who can join

Age: 12 and older, up to 24. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• Negative serum or urine pregnancy test if not sterilized
• Tanner Stage 4 or 5
• Accessible medical and medication history
• Willing to fast and complete clinical and laboratory evaluations
• Willingness and ability to give consent or assent with parental permission

You may not qualify if…

• Refusal to fast for 8 hours prior to specimen collection
• Unable to obtain history
• Pregnancy in last 12 months or currently pregnant
• History of anorexia or bulimia
• Type I Diabetes mellitus
• Type II Diabetes mellitus and cannot omit medication for the 48 hour period prior to laboratory specimen collection

Where it is running

• Children's Hopsital of Los Angeles — Los Angeles, California, United States
• University of California at San Diego — San Diego, California, United States
• Children's National Medical Center — Washington D.C., District of Columbia, United States
• Children's Diagnostic and Treatment Center — Fort Lauderdale, Florida, United States
• University of Miami — Miami, Florida, United States
• University of South Florida — Tampa, Florida, United States
• Stoger Hospital of Cook County — Chicago, Illinois, United States
• Tulane University — New Orleans, Louisiana, United States
• Mt. Sinai Hospital — New York, New York, United States
• Montefiore Medical Center — The Bronx, New York, United States
• Children's Hospital of Philadelphia — Philadelphia, Pennsylvania, United States

Full record on ClinicalTrials.gov

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