Ginger Control of Chemotherapy Induced Nausea and Vomiting

Completed · Phase 2

Conditions studied: Nausea, Vomiting, Chemotherapy

In brief

This is a trial to determine the safety and efficacy of ginger in reducing the prevalence and severity of chemotherapy induced nausea and vomiting.

Key facts

Study ID

NCT00065221

Run by

National Center for Complementary and Integrative Health (NCCIH)

People needed

180

Starts

2003-06-01

Expected to finish

2007-01-01

Last updated by the study team

2008-01-25

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Confirmed diagnosis of cancer and currently receiving chemotherapy
• Currently being treated with any chemotherapeutic agent at any dose, and have experienced nausea and/or vomiting from a previous round of chemothearpy
• Scheduled to receive a 5-HT3 receptor antagonist antiemetic: ondansetron (Zofran®) granistron (Kytril®), tropisetron (Navoban®) or dolasetron mesylate (Anzemet®), palanosetron (Alozi) and/or the NK1 antagonist aprepitant (Emend)
• Must be able to swallow capsules
• Must be able to understand English or Spanish, complete questionnaires in English or Spanish
• Women of childbearing age to use appropriate birth control

You may not qualify if…

• Chemotherapy regimens with multiple-day doses
• Clinical evidence of current or impending bowel obstruction or symptomatic brain metastases
• Concurrent radiotherapy that is classified as high or intermediate risk of causing nausea and vomiting; total body irradiation, hemi-body, upper abdomen, abdominal-pelvic mantle, cranium, craniospinal irradiation
• Pregnant or lactating
• Patients with a history of a bleeding disorder(s) or those experiencing thrombocytopenia
• Currently be taking ginger or have taken ginger in the last month
• Have an allergy to ginger

Where it is running

• Northern Indiana Cancer Research Consortium CCOP — South Bend, Indiana, United States
• University of Michigan Cancer Center Complementary and Alternative Medicine Research Center — Ann Arbor, Michigan, United States
• St. Joseph Mercy Hospital — Ann Arbor, Michigan, United States
• Community Clinic Oncology Program — Grand Rapids, Michigan, United States
• Our Lady of Mercy Medical Center, Comprehensive Cancer Center — The Bronx, New York, United States
• Community Clinic Oncology Program — San Juan, Puerto Rico

Full record on ClinicalTrials.gov

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