Endometrial Biopsy in Infertile Patients

Completed · Phase 3

Conditions studied: Infertility

In brief

When a woman becomes pregnant, the fertilized egg attaches itself to the lining of the uterus (endometrium). The endometrium is constantly changing throughout a woman's menstrual cycle in response to the female hormones estrogen and progesterone. The endometrium must have certain characteristics (be at a specific phase in its cycle) in order for the fertilized egg to successfully attach. Infertility may be caused by an "out of phase" endometrium (i.e., the endometrium doesn't have the right characteristics when the fertilized egg reaches it). The purpose of this study is to evaluate whether the endometrial biopsy is useful in predicting the potential for becoming pregnant and bearing a child.

Key facts

Study ID

NCT00064935

Run by

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

People needed

880

Starts

1999-04-01

Expected to finish

2002-02-01

Last updated by the study team

2005-06-24

Who can join

Age: 25 and older, up to 39. Sex: female. Healthy volunteers: accepted.

Where it is running

• University of Alabama — Birmingham, Alabama, United States
• University of Colorado — Denver, Colorado, United States
• Wayne State University — Detroit, Michigan, United States
• University of Medicine and Dentistry, NJ — Newark, New Jersey, United States
• Pennsylvania State University — Hershey, Pennsylvania, United States
• University of Pennsylvania — Philadelphia, Pennsylvania, United States
• University of Texas Southwestern Medical Center — Dallas, Texas, United States
• Baylor College of Medicine — Houston, Texas, United States

Full record on ClinicalTrials.gov

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