Alzheimer's Disease Genetics Study

Recruiting now

Conditions studied: Alzheimer Disease, Late Onset Alzheimer Disease, Dementia

In brief

The purpose of the Alzheimer's Disease Genetics Study is to identify the genes that are responsible for causing Alzheimer's Disease (AD). One of the ways in which the risk factor genes for late onset AD can be investigated is by identifying and collecting genetic material from families with multiple members diagnosed with AD or dementia.

Key facts

Study ID

NCT00064870

Run by

Indiana University

People needed

10000

Starts

2002-06-01

Expected to finish

2026-07-01

Last updated by the study team

2025-10-01

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Two living family members diagnosed with AD or other dementia with any age of onset
• Biological samples available
• Fresh blood, or
• Immortalized lymphoblastic cell lines, or
• 3-5 grams of frozen cerebral cortex; fixed samples are not accepted
• Please note: this study does not include genetic counseling; because no personal identifying information such as name or date of birth is attached to samples, results of individual tests are not available to participants or family members.

You may not qualify if…

• Does not meet inclusion criteria
• Member of a family that was included in the National Institute of Mental Health AD Genetics Sib Pair collection

Where it is running

• Participants are being recruited from all over the United States — Nationwide, Indiana, United States (enrolling)

Full record on ClinicalTrials.gov

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