Noninvasive Prenatal Diagnosis: Using Fetal Cells From Maternal Blood

Status unconfirmed

Conditions studied: Chromosome Disorders

In brief

This purpose of this study is to develop noninvasive methods of prenatal diagnosis. Fetal cells can be found in maternal blood. This study is designed to isolate these fetal cells from a sample of the pregnant woman's blood and use those cells to test for fetal chromosome abnormalities.

Key facts

Study ID

NCT00064597

Run by

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

People needed

3500

Starts

1987-12-01

Expected to finish

2003-12-01

Last updated by the study team

2005-06-24

Who can join

Age: 16 and older, up to 45. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• Pregnant
• Abnormal serum marker profile (alpha-fetoprotein, hCG, estriol)
• Ultrasound abnormalities of the fetus
• Any high risk indicator for aneuploidy as determined by physician

Where it is running

• University of Illinois at Chicago — Chicago, Illinois, United States
• New England Medical Center Hospital — Boston, Massachusetts, United States
• Wayne State University — Detroit, Michigan, United States
• Jefferson Medical College — Philadelphia, Pennsylvania, United States
• Baylor College of Medicine — Houston, Texas, United States

Full record on ClinicalTrials.gov

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