S0115, High-Dose Melphalan and Autologous Peripheral Stem Cell Transplantation in Treating Patients With Multiple Myeloma or Primary Systemic Amyloidosis
Completed · Phase 2
Conditions studied: Multiple Myeloma, Plasma Cell Myeloma
In brief
RATIONALE: Drugs used in chemotherapy such as melphalan work in different ways to stop cancer cells from dividing so they stop growing or die. Combining chemotherapy with donor peripheral stem cell transplantation may allow the doctor to give higher doses of chemotherapy drugs and kill more cancer cells. PURPOSE: This phase II trial is studying how well giving melphalan together with autologous stem cell transplantation works in treating patients with multiple myeloma or primary systemic amyloidosis.
Key facts
- Study ID
- NCT00064337
- Run by
- SWOG Cancer Research Network
- People needed
- 104
- Starts
- 2004-01-01
- Expected to finish
- 2015-11-01
- Last updated by the study team
- 2018-08-09
Who can join
Age: 18 and older, up to 120. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Arkansas Cancer Research Center at University of Arkansas for Medical Sciences — Little Rock, Arkansas, United States
- University of California Davis Cancer Center — Sacramento, California, United States
- Mountain States Tumor Institute at St. Luke's Regional Medical Center — Boise, Idaho, United States
- Kansas Masonic Cancer Research Institute at the University of Kansas Medical Center — Kansas City, Kansas, United States
- Tammy Walker Cancer Center at Salina Regional Health Center — Salina, Kansas, United States
- Boston University Cancer Research Center — Boston, Massachusetts, United States
- Barbara Ann Karmanos Cancer Institute — Detroit, Michigan, United States
- Josephine Ford Cancer Center at Henry Ford Hospital — Detroit, Michigan, United States
- CCOP - Montana Cancer Consortium — Billings, Montana, United States
- Hematology-Oncology Centers of the Northern Rockies - Billings — Billings, Montana, United States
- Northern Rockies Radiation Oncology Center — Billings, Montana, United States
- Billings Clinic - Downtown — Billings, Montana, United States
- Bozeman Deaconess Cancer Center — Bozeman, Montana, United States
- St. James Healthcare Cancer Care — Butte, Montana, United States
- Big Sky Oncology — Great Falls, Montana, United States
- Great Falls Clinic - Main Facility — Great Falls, Montana, United States
- Sletten Cancer Institute at Benefis Healthcare — Great Falls, Montana, United States
- Study site — Great Falls, Montana, United States
- Northern Montana Hospital — Havre, Montana, United States
- St. Peter's Hospital — Helena, Montana, United States
- Glacier Oncology, PLLC — Kalispell, Montana, United States
- Kalispell Medical Oncology at KRMC — Kalispell, Montana, United States
- Guardian Oncology and Center for Wellness — Missoula, Montana, United States
- Montana Cancer Specialists at Montana Cancer Center — Missoula, Montana, United States
- Montana Cancer Center at St. Patrick Hospital and Health Sciences Center — Missoula, Montana, United States
Full record on ClinicalTrials.gov
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