Bortezomib With or Without Docetaxel in Treating Patients With Relapsed or Refractory Advanced Non-Small Cell Lung Cancer
Completed · Phase 2
Conditions studied: Lung Cancer
In brief
RATIONALE: Drugs used in chemotherapy such as docetaxel use different ways to stop tumor cells from dividing so they stop growing or die. Bortezomib may stop the growth of cancer cells by blocking the enzymes necessary for cancer cell growth. It is not yet known whether bortezomib is more effective with or without docetaxel in treating patients with advanced non-small cell lung cancer. PURPOSE: Randomized phase II trial to compare the effectiveness of bortezomib with or without docetaxel in treating patients who have relapsed or refractory stage IIIB or stage IV non-small cell lung cancer.
Key facts
- Study ID
- NCT00064012
- Run by
- University of Wisconsin, Madison
- People needed
- 4
- Starts
- 2003-05-01
- Expected to finish
- 2004-07-01
- Last updated by the study team
- 2019-12-13
Who can join
Age: 18 and older, up to 120. Sex: any. Healthy volunteers: not accepted.
Where it is running
- University of Alabama at Birmingham Comprehensive Cancer Center — Birmingham, Alabama, United States
- Cedars-Sinai Comprehensive Cancer Center at Cedars-Sinai Medical Center — Los Angeles, California, United States
- Jonsson Comprehensive Cancer Center, UCLA — Los Angeles, California, United States
- University of Colorado Cancer Center at University of Colorado Health Sciences Center — Aurora, Colorado, United States
- Yale Comprehensive Cancer Center — New Haven, Connecticut, United States
- University of Miami Sylvester Cancer Center — Miami, Florida, United States
- Winship Cancer Institute of Emory University — Atlanta, Georgia, United States
- Veterans Affairs Medical Center - Atlanta (Decatur) — Decatur, Georgia, United States
- Massachusetts General Hospital Cancer Center — Boston, Massachusetts, United States
- Dana-Farber/Harvard Cancer Center at Dana Farber Cancer Institute — Boston, Massachusetts, United States
- Hubert H. Humphrey Cancer Center at North Memorial Medical Center — Robbinsdale, Minnesota, United States
- Kansas City Cancer Centers - Central — Kansas City, Missouri, United States
- Siteman Cancer Center — St Louis, Missouri, United States
- St. Louis University Hospital Cancer Center — St Louis, Missouri, United States
- Blumenthal Cancer Center at Carolinas Medical Center — Charlotte, North Carolina, United States
- Duke Comprehensive Cancer Center — Durham, North Carolina, United States
- Kimmel Cancer Center at Thomas Jefferson University - Philadelphia — Philadelphia, Pennsylvania, United States
- Vanderbilt-Ingram Cancer Center at Vanderbilt Medical Center — Nashville, Tennessee, United States
- University of Texas - MD Anderson Cancer Center — Houston, Texas, United States
- Huntsman Cancer Institute — Salt Lake City, Utah, United States
- University of Wisconsin Comprehensive Cancer Center — Madison, Wisconsin, United States
Full record on ClinicalTrials.gov
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