Interstitial Brachytherapy With or Without External-Beam Radiation Therapy in Treating Patients With Prostate Cancer

Completed · Phase 3

Conditions studied: Prostate Cancer

In brief

RATIONALE: Radiation therapy uses high-energy x-rays and other sources to damage tumor cells. Interstitial brachytherapy uses radioactive material placed directly into or near a tumor to kill tumor cells. Combining interstitial brachytherapy with external-beam radiation therapy may kill more tumor cells. It is not yet known whether interstitial brachytherapy is more effective with or without external-beam radiation therapy in treating prostate cancer. PURPOSE: Randomized phase III trial to compare the effectiveness of interstitial brachytherapy with or without external-beam radiation therapy in treating patients who have prostate cancer.

Key facts

Study ID

NCT00063882

Run by

Radiation Therapy Oncology Group

People needed

588

Starts

2003-06-01

Expected to finish

2022-12-22

Last updated by the study team

2026-03-05

Who can join

Age: 18 and older, up to 120. Sex: male. Healthy volunteers: not accepted.

Where it is running

• Auburn Radiation Oncology — Auburn, California, United States
• Alta Bates Summit Comprehensive Cancer Center — Berkeley, California, United States
• Peninsula Medical Center — Burlingame, California, United States
• Radiation Oncology Centers - Cameron Park — Cameron Park, California, United States
• Mercy Cancer Center at Mercy San Juan Medical Center — Carmichael, California, United States
• East Bay Radiation Oncology Center — Castro Valley, California, United States
• Valley Medical Oncology Consultants - Castro Valley — Castro Valley, California, United States
• Valley Medical Oncology — Fremont, California, United States
• California Cancer Center - Woodward Park Office — Fresno, California, United States
• Kaiser Permanente Medical Center - Hayward — Hayward, California, United States
• Contra Costa Regional Medical Center — Martinez, California, United States
• El Camino Hospital Cancer Center — Mountain View, California, United States
• Sutter Health - Western Division Cancer Research Group — Novato, California, United States
• Alta Bates Summit Medical Center - Summit Campus — Oakland, California, United States
• Bay Area Breast Surgeons, Incorporated — Oakland, California, United States
• CCOP - Bay Area Tumor Institute — Oakland, California, United States
• Larry G Strieff MD Medical Corporation — Oakland, California, United States
• Tom K Lee, Incorporated — Oakland, California, United States
• Kaiser Permanente - Division of Research - Oakland — Oakland, California, United States
• Kaiser Permanente Medical Center - Oakland — Oakland, California, United States
• Kaiser Permanente Medical Center - Rancho Cordova — Rancho Cordova, California, United States
• Kaiser Permanente Medical Center - Redwood City — Redwood City, California, United States
• Kaiser Permanente Medical Center - Richmond — Richmond, California, United States
• Rohnert Park Cancer Center — Rohnert Park, California, United States
• Arizona Oncology Services Foundation — Phoenix, Arizona, United States

Full record on ClinicalTrials.gov

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