PET Imaging of Dopamine in Healthy Study Participants
Completed · Phase 2
Conditions studied: Healthy
In brief
The purpose of this study is to measure molecules on or in cells that interact with a chemical in the nervous system, called dopamine. Investigators will obtain two kinds of images of the brain-a position emission tomography (PET) scan and a magnetic resonance imaging (MRI) scan. Thirty-eight participants aged 18 to 45 will be enrolled in this study. They must have no history of medical or psychiatric illness, including substance abuse. Participants will have four appointments at NIH. On the first visit, they will undergo a physical exam, a medical history, and lab tests. The second and third visits will involve PET scans and the fourth visit will involve an MRI scan. Participants will be compensated up to $430 for their involvement in this study.
Key facts
- Study ID
- NCT00062946
- Run by
- National Institute of Mental Health (NIMH)
- People needed
- 45
- Starts
- 2003-06-17
- Expected to finish
- 2007-08-15
- Last updated by the study team
- 2017-07-02
Who can join
Age: 18 and older, up to 45. Sex: any. Healthy volunteers: accepted.
You may not qualify if…
- Pregnancy/Nursing
- Evidence of active mental or neurological illness
- Medically significant biochemical or hematological abnormality on screening laboratory studies
- Abnormal ECG
- High Blood Pressure (above 140 systolic and/or above 90 dystolic pressure)
- History of myocardial infarction or angina pectoris
- Positive urine drug screen or use of alcohol within one week prior to each PET study
- History of substance abuse or dependence within 6 months
- Presence of ferromagnetic metal in the body or heart pacemaker
- Body weight more than 93 kg to limit AMPT dose to 4 g/ day (only for subjects having four PET scans and d-amphetamine and AMPT administration)
- Claustrophobia
Where it is running
- National Institutes of Health Clinical Center, 9000 Rockville Pike — Bethesda, Maryland, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.